{"title":"COVID-19血液透析患者死亡率相关因素","authors":"G. Yilmaz, O. Timur","doi":"10.34172/jrip.2022.32005","DOIUrl":null,"url":null,"abstract":"Introduction: The mortality rate in COVID-19 patients is about 2%, however advanced age, male gender, comorbid diseases increase the risk of mortality. Patients with end-stage renal disease (ESRD) and hemodialysis (HD) treatment are more susceptible to infection due to both existing comorbid diseases and immune suppression caused by uremia. Objectives: This study aims to show the potential of easily obtainable, inexpensive and reproducible markers in predicting mortality in HD patients at the time of diagnosis. Patients and Methods: In this study, we examined the relationship between; neutrophil to lymphocyte ratio (NLR), mean platelet volume (MPV) and C-reactive protein (CRP)/albumin values at the time of hospital admission with mortality in 75 HD patients diagnosed with COVID-19. All analyses were conducted using IBM SPSS Statistics 21.0 and MS-Excel 2010 software. Results: A total of 75 HD patients diagnosed with COVID-19 were included in the study. Out of these, at least 19 (25.3%) patients received hydroxychloroquine, 68 (90.6%) patients favipiravir, two (2.6%) patients tocilizumab and two patients (2.6%) immune plasma therapy. Among these patients, sixteen patients (21.3%) needed invasive mechanic ventilation, eight patients (10.6%) needed high flow oxygen and seven patients (9.3%) needed non-invasive mechanic ventilation and 17 of 75 patients (23%) died. A total of 14 of the 17 non-survivors were intubated. In comparison between survivors and non-survivors in our study; NLR, MPV, CRP, CRP/albumin and phosphorus values were significantly higher in the non-survivors group. Conclusion: According to this study, NLR, MPV and CRP/albumin values are associated with mortality in HD patients affected with COVID-19.","PeriodicalId":16950,"journal":{"name":"Journal of Renal Injury Prevention","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Factors related to mortality in hemodialysis patients with COVID-19\",\"authors\":\"G. Yilmaz, O. Timur\",\"doi\":\"10.34172/jrip.2022.32005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: The mortality rate in COVID-19 patients is about 2%, however advanced age, male gender, comorbid diseases increase the risk of mortality. Patients with end-stage renal disease (ESRD) and hemodialysis (HD) treatment are more susceptible to infection due to both existing comorbid diseases and immune suppression caused by uremia. Objectives: This study aims to show the potential of easily obtainable, inexpensive and reproducible markers in predicting mortality in HD patients at the time of diagnosis. Patients and Methods: In this study, we examined the relationship between; neutrophil to lymphocyte ratio (NLR), mean platelet volume (MPV) and C-reactive protein (CRP)/albumin values at the time of hospital admission with mortality in 75 HD patients diagnosed with COVID-19. All analyses were conducted using IBM SPSS Statistics 21.0 and MS-Excel 2010 software. Results: A total of 75 HD patients diagnosed with COVID-19 were included in the study. Out of these, at least 19 (25.3%) patients received hydroxychloroquine, 68 (90.6%) patients favipiravir, two (2.6%) patients tocilizumab and two patients (2.6%) immune plasma therapy. Among these patients, sixteen patients (21.3%) needed invasive mechanic ventilation, eight patients (10.6%) needed high flow oxygen and seven patients (9.3%) needed non-invasive mechanic ventilation and 17 of 75 patients (23%) died. A total of 14 of the 17 non-survivors were intubated. In comparison between survivors and non-survivors in our study; NLR, MPV, CRP, CRP/albumin and phosphorus values were significantly higher in the non-survivors group. Conclusion: According to this study, NLR, MPV and CRP/albumin values are associated with mortality in HD patients affected with COVID-19.\",\"PeriodicalId\":16950,\"journal\":{\"name\":\"Journal of Renal Injury Prevention\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2022-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Renal Injury Prevention\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.34172/jrip.2022.32005\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Renal Injury Prevention","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34172/jrip.2022.32005","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Factors related to mortality in hemodialysis patients with COVID-19
Introduction: The mortality rate in COVID-19 patients is about 2%, however advanced age, male gender, comorbid diseases increase the risk of mortality. Patients with end-stage renal disease (ESRD) and hemodialysis (HD) treatment are more susceptible to infection due to both existing comorbid diseases and immune suppression caused by uremia. Objectives: This study aims to show the potential of easily obtainable, inexpensive and reproducible markers in predicting mortality in HD patients at the time of diagnosis. Patients and Methods: In this study, we examined the relationship between; neutrophil to lymphocyte ratio (NLR), mean platelet volume (MPV) and C-reactive protein (CRP)/albumin values at the time of hospital admission with mortality in 75 HD patients diagnosed with COVID-19. All analyses were conducted using IBM SPSS Statistics 21.0 and MS-Excel 2010 software. Results: A total of 75 HD patients diagnosed with COVID-19 were included in the study. Out of these, at least 19 (25.3%) patients received hydroxychloroquine, 68 (90.6%) patients favipiravir, two (2.6%) patients tocilizumab and two patients (2.6%) immune plasma therapy. Among these patients, sixteen patients (21.3%) needed invasive mechanic ventilation, eight patients (10.6%) needed high flow oxygen and seven patients (9.3%) needed non-invasive mechanic ventilation and 17 of 75 patients (23%) died. A total of 14 of the 17 non-survivors were intubated. In comparison between survivors and non-survivors in our study; NLR, MPV, CRP, CRP/albumin and phosphorus values were significantly higher in the non-survivors group. Conclusion: According to this study, NLR, MPV and CRP/albumin values are associated with mortality in HD patients affected with COVID-19.
期刊介绍:
The Journal of Renal Injury Prevention (JRIP) is a quarterly peer-reviewed international journal devoted to the promotion of early diagnosis and prevention of renal diseases. It publishes in March, June, September and December of each year. It has pursued this aim through publishing editorials, original research articles, reviews, mini-reviews, commentaries, letters to the editor, hypothesis, case reports, epidemiology and prevention, news and views and renal biopsy teaching point. In this journal, particular emphasis is given to research, both experimental and clinical, aimed at protection/prevention of renal failure and modalities in the treatment of diabetic nephropathy. A further aim of this journal is to emphasize and strengthen the link between renal pathologists/nephropathologists and nephrologists. In addition, JRIP welcomes basic biomedical as well as pharmaceutical scientific research applied to clinical nephrology. Futuristic conceptual hypothesis that integrate various fields of acute kidney injury and renal tubular cell protection are encouraged to be submitted.