细针吸细胞学上的朗格汉斯细胞组织细胞增多症

Pub Date : 2017-09-01 DOI:10.12816/0047637

S. Shaikh, Eman Al Jufairi, Rabab Al Khayyat

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引用次数: 0

摘要

175 LCH是一种罕见疾病，主要影响儿童和年轻人。LCH被认为是一种单核吞噬免疫调节系统的肿瘤。其特点是朗格汉斯细胞(LCs)的克隆性增殖。LCH有三种类型:嗜酸性肉芽肿(孤立且最常见)、Hand-Schuller-Christian病(多灶单系统形式)和letter - siwe综合征(多灶多系统形式)1,2。LCH的诊断细胞学特征包括高细胞密度，由特征性的朗格汉斯细胞片组成，具有大的肾形细胞核，混合着嗜酸性粒细胞、中性粒细胞、巨噬细胞和淋巴细胞。

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Langerhans Cell Histiocytosis on Fine Needle Aspiration Cytology

175 LCH is a rare disease affecting predominantly children and young adults. LCH is considered a neoplasm of the mononuclear phagocytic immunoregulatory system. It is characterized by clonal proliferation of Langerhans cells (LCs). LCH has three categories: eosinophilic granuloma (solitary and most common), Hand-Schuller-Christian disease (multifocal unisystem form) and Letterer-Siwe syndrome (multifocal multisystem form)1,2. The diagnostic cytological features of LCH include high cellularity composed of sheets of characteristic Langerhans cell with large kidney-shaped nuclei admixed with eosinophils, neutrophils, macrophages, and lymphocytes.

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