综合征和非综合征患者牙源性角化囊肿的复发模式

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Journal of Maxillofacial & Oral Surgery Pub Date : 2024-02-01 Epub Date: 2023-04-24 DOI:10.1007/s12663-023-01920-9
Tim Van Cleemput, Xander Jackers, Maria Piagkou, Constantinus Politis
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引用次数: 0

摘要

目的:牙源性角囊肿(OKCs)的复发率很高。我们旨在确定OKC的复发模式,以及非综合征和综合征患者中第二原发性OKC的发病情况:我们使用人口统计学、临床(年龄、性别、位置和大小)、组织病理学、放射学和治疗数据,对 1998 年至 2021 年(23 年)向我科报告的 OKC 患者进行了回顾性评估。所有患者均接受了 3 年以上的随访,并对 OKC 复发情况进行了评估。对患有无色素性基底细胞癌综合征(NBCCS)的患者进行了单独评估:我们在非综合征和综合征 OKC 组中分别纳入了 38 名和 13 名患者。非综合征组和综合征组的复发率分别为 15.8% 和 21.4%;8.9% 的患者第二次复发,1.8% 的患者第三次复发。非综合征组中没有观察到第二个原发性 OKC,而综合征组中 76.9% 的患者至少出现了一个原发性 OKC:我们发现,与非综合征 OKCs 患者相比,NBCCS 患者的复发率更高(21.4% 对 15.8%)。与非综合征 OKC 患者相比,NBCCS 患者再次发生原发性 OKC 的概率更高(76.9% 对 0%)。没有发现具有统计学意义的 OKC 复发风险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recurrence Patterns of Odontogenic Keratocysts in Syndromic and Non-Syndromic Patients.

Purpose: Odontogenic keratocysts (OKCs) have high recurrence rates. We aimed to identify recurrence patterns in OKCs and the onset of second primary OKCs in non-syndromic and syndromic patients.

Material and methods: Patients with OKCs reporting to our department from 1998 to 2021 (23 years) were retrospectively evaluated using demographic, clinical (age, sex, location, and size), histopathological, radiographic, and treatment data. All patients were followed-up for > 3 years and evaluated for OKC recurrence. Patients with naevoid basal cell carcinoma syndrome (NBCCS) were evaluated separately.

Results: We included 38 and 13 patients in the non-syndromic and syndromic OKC groups, respectively. The recurrence rates were 15.8 and 21.4% in the non-syndromic and syndromic groups, respectively; 8.9% of patients exhibited a second recurrence and 1.8% a third recurrence. No second primary OKCs were observed in the non-syndromic group; 76.9% of patients in the syndromic group developed at least one.

Conclusion: We found a higher recurrence rate in patients with NBCCS compared with patients with non-syndromic OKCs (21.4 versus 15.8%). The probability of developing a second primary OKC in patients with NBCCS was higher compared with that in patients with non-syndromic OKCs (76.9 versus 0%). No statistically significant risk factors for OKC recurrence were identified.

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来源期刊
Journal of Maxillofacial & Oral Surgery
Journal of Maxillofacial & Oral Surgery DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
1.90
自引率
0.00%
发文量
138
期刊介绍: This journal offers comprehensive coverage of new techniques, important developments and innovative ideas in Oral and Maxillofacial Surgery. Practice-applicable articles help develop the methods used to handle dentoalveolar surgery, facial injuries and deformities, TMJ disorders, oral cancer, jaw reconstruction, anesthesia and analgesia. The journal also includes specifics on new instruments, diagnostic equipment’s and modern therapeutic drugs and devices. Journal of Oral and Maxillofacial Surgery is recommended for first or priority subscription by the Dental Section of the Medical Library Association. Specific topics covered recently have included: ? distraction osteogenesis ? synthetic bone substitutes ? fibroblast growth factors ? fetal wound healing ? skull base surgery ? computer-assisted surgery ? vascularized bone grafts Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.
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