男性多尿:一例原发性干燥综合征

D. Satharasinghe, S. H. Atukorale, P. Weerawansa, H. Senanayake
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引用次数: 0

摘要

干燥综合征是一种慢性自身免疫性疾病,伴有淋巴细胞浸润外分泌腺,引起口腔和眼部干燥,并有公认的全身表现。虽然原发性干燥综合征(pSS)在女性中很常见,但在男性中却没有得到很好的认识。据我们所知,这是斯里兰卡男性首次报告pSS病例。男性,58岁,多尿。他有六个月的干燥症状,多尿是继发于为缓解口腔干燥而增加饮水量。检查发现双侧唾液腺肿大,触痛。排除继发性原因后,诊断为pSS。治疗开始使用类固醇、硫唑嘌呤和对症治疗。原发性干燥综合征是一种被忽视的诊断,特别是在男性中,由于其多器官累及,导致发病率增加。认识和支持治疗有助于提高患者的生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A male presenting with polyuria: a case of primary Sjögren syndrome
Sjogren syndrome is a chronic autoimmune disorder with lymphocytic infiltration of exocrine glands causing oral and ocular dryness and well recognized systemic manifestations. Although primary Sjogren syndrome (pSS) is common in women, it is not well recognized in men. This is the first reported case of pSS in a Sri Lankan male to the best of our knowledge. A 58-year-old man presented with polyuria. He has had sicca symptoms for six months and polyuria was secondary to the increased water intake to relieve oral dryness. Examination revealed enlarged tender bilateral salivary glands. After excluding secondary causes, he was diagnosed with pSS. The treatment commenced with steroids, azathioprine, and symptomatic therapy. Primary Sjogren syndrome is an overlooked diagnosis, especially in men, leading to increased morbidity given its multi-organ involvement. Recognition and supportive therapy can help to improve the quality of life of patients.
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