冷冻干燥法制备新型骨科多孔石墨烯支架——GDQ方法的制备和屈曲模拟

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Shahin Foroutan, M. Hashemian, A. Khandan
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引用次数: 13

摘要

本文采用冷冻干燥技术制备了一种由海藻酸钠聚合物、石墨烯纳米片和硅灰石粉末制成的新型生物纳米复合材料样品。使用拉伸强度和生物测试对样品进行机械和生物评估。通过X射线衍射(XRD)和扫描电子显微镜(SEM)研究进行了相和拓扑表征。随后,利用Euler-Bernoulli和Timoshenko梁(EBT和TBT)理论,分析了多孔仿生复合软组织在石墨烯含量方面的屈曲响应。为了求解控制方程,提出了一个充分的数值解。从实验测试中提取了多孔仿生复合材料的弹性模量和质量密度。所获得的结果表明,具有1wt.%石墨烯片的样品显示出适当的机械和生物特征。因此,具有1wt.%石墨烯片的样品可以用作轻质骨替代物应用的潜在案例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Novel Porous Graphene Scaffold Prepared Using Freeze-drying Technique for Orthopedic Approaches: Fabrication and Buckling Simulation Using GDQ Method
In this article, a novel bio-nanocomposite sample made of sodium alginate polymer, graphene nanosheets and wollastonite powder were produced using freeze-drying technique. The samples were mechanically and biologically evaluated using tensile strength and biological test. The phase and topological characterization were conducted by performing X-ray diffraction (XRD) and scanning electron microscopy (SEM) studies. Subsequently, using Euler-Bernoulli and Timoshenko beam (EBT and TBT) theories, the buckling response of the porous bionanocomposite soft tissue were analyzed with respect to graphene content. In order to solve the governing equations a sufficient numerical solution is proposed. Elastic modulus and mass density of the porous bionanocomposite are extracted from the experimental tests. The obtained results indicated the sample with 1 wt.% graphene sheet showed proper mechanical and biological features. Therefore, the sample with 1 wt.% graphene sheet can be used as potential case for light weight bone substitute applications.
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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