评估肝肿瘤经桡动脉介入栓塞安全性和有效性的回顾性比较研究:单一手术经验

R. Sundareyan, S. Karkhanis
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引用次数: 0

摘要

目的评价经桡动脉栓塞(TRA)治疗肝肿瘤栓塞的有效性和安全性,并比较TRA与经股动脉栓塞(TFA)的疗效。材料与方法回顾性分析2017年11月至2019年4月同一术者通过TFA或TRA连续进行的所有肝脏肿瘤栓塞手术。记录程序变量,包括透视时间、辐射剂量(参考风量[RAK])、转换率和并发症发生率以及患者偏好。主要终点是技术上的成功,即栓塞手术的成功完成。程序变量包括辐射暴露和患者偏好,以及并发症作为次要终点进行分析。结果90例102例手术中,44例经TFA治疗,其余经TRA治疗。TRA的技术成功率为98.2%,交叉率为1.7%。两组无大血管并发症,轻微并发症发生率相似(TRA组为8.6%,TFA组为2.3%;P = 0.055),无临床后遗症。在最初的学习曲线之后,两个访问站点之间没有注意到其他程序变量的显着差异。经TRA后行走速度加快(P < 0.055)。所有12名患者在首次TRA后再次接受TACE,而不是TFA。结论TRA用于肝肿瘤栓塞是安全有效的。它的安全性和有效性与TFA相当,增加了患者的舒适度和更快的行走速度。新的导管选择和现有技术的改进,在这篇文章中解释了桡动脉进入是一种安全有效的替代肝动脉栓塞。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Retrospective Comparative Study to Assess the Safety and Efficacy of Transradial Arterial Access for Hepatic Tumor Embolizations: A Single Operator Experience
Abstract Objectives To assess the efficacy and safety of transradial arterial access (TRA) for hepatic tumor embolizations and compare the outcomes between the TRA and transfemoral arterial access (TFA). Materials and Methods  A retrospective analysis of all consecutive hepatic tumor embolization procedures done through TFA or TRA by a single operator from November 2017 to April 2019 was performed. The procedural variables, including fluoroscopy time, radiation dose (reference air kerma [RAK]), conversion and complication rates, and patient preferences were recorded. The primary endpoint was technical success, which was defined as the successful completion of the embolization procedure. Procedural variables including radiation exposure and patient preferences, and complications were analyzed as secondary endpoints. Results  Out of 102 procedures in 90 patients, 44 were performed through TFA and the rest by TRA. A technical success rate of 98.2% and a crossover rate of 1.7% were recorded for TRA. There were no major vascular complications and similar rates of minor complications (8.6% for TRA, 2.3% for TFA; P  = 0.055), without any clinical sequelae. After the initial learning curve, no significant differences for other procedural variables were noted between the two access sites. Faster ambulation were achieved following TRA ( P  < 0.055). All 12 patients who underwent repeat TACE after initial TRA chose this again over TFA. Conclusions  TRA is safe and effective for hepatic tumor embolization. Its safety and efficacy profile is comparable to that of TFA, with added improved patient comfort and faster ambulation. Advances in Knowledge  New catheter options and modifications of the existing techniques as explained in this article proved radial arterial access as a safe and effective alternative in hepatic arterial embolization.
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