Hailey-Hailey Disease Treated Successfully with Acitretin

Hailey-Hailey disease (HHD) is a rare genodermatosis characterized by acantholysis and dyskeratosis of the intertriginous areas. This article presents the case of a 41-year-old Bahraini male, not known to have any medical illness, who presented with a two-year history of bilateral, painful, fissured skin lesions on the groin and axilla. The diagnosis of HHD was confirmed by biopsy. The patient was treated with a course of acitretin 25mg once daily orally for three months, and the treatment led to significant improvement. Up to date, this is the first case to be reported in Bahrain. The case report demonstrated the benefit of using acitretin in the management of HHD. Keywords: Acantholysis, Acitretin, Axilla, Benign Familial Pemphigus, Groin, Skin Disease