案例研究:深度吸气屏气治疗左侧乳腺癌的VMAT、IMRT和3DCRT剂量学比较

IF 0.6 Q3 ENGINEERING, MULTIDISCIPLINARY

Acta Polytechnica Pub Date : 2023-05-02 DOI:10.14311/ap.2023.63.0123

T. Hanušová

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引用次数: 0

摘要

本案例研究的目的是比较左侧乳腺癌症（深吸气呼气孔（DIBH）中无阳性淋巴结的整个乳房）患者的3D适形放射治疗（3DCRT）计划与体积调制电弧治疗（VMAT）和强度调制放射治疗（IMRT）计划。最初的临床计划使用切向场中3DCRT技术，结合6MV和18MV光子束。VMAT和IMRT计划基于先前发表的几种技术，并使用了6MV波束。本病例研究包括两名患者，并为每名患者创建4个计划并进行比较。所有计划都在肿瘤覆盖率、梯度测量和一致性指数、危险器官剂量（OAR）、接受5Gy的身体体积以及监测单位数量（MU）方面进行了比较。虽然IMRT和VMAT计划实现了更好的肿瘤覆盖率和一致性，但3DCRT技术更好地避免了OAR，这也导致了最低剂量的浴和MU数量。

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Case study: Dosimetric comparison of VMAT, IMRT and 3DCRT techniques for left-sided breast cancer treated in deep inspiration breath-hold

The aim of this case study was to compare 3D conformal radiotherapy (3DCRT) plans for patients treated for left-sided breast cancer (whole breast without positive lymph nodes in deep inspiration breath-hold (DIBH)) to volumetric modulated arc therapy (VMAT) and intensity modulated radiation therapy (IMRT) plans. The original clinical plans used tangential field-in-field 3DCRT technique with a combination of 6 MV and 18 MV photon beams. VMAT and IMRT plans were based on several previously published techniques and used 6 MV beams. Two patients were included in this case study and 4 plans were created and compared for each one. All plans were compared in terms of tumour coverage, gradient measure and conformity index, doses to organs at risk (OARs), the volume of body receiving 5 Gy and also the number of Monitor Units (MUs). While better tumour coverage and conformity was achieved with IMRT and VMAT plans, OARs were better spared with the 3DCRT technique, which also resulted in the lowest dose bath and number of MUs.

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来源期刊

Acta Polytechnica ENGINEERING, MULTIDISCIPLINARY-

CiteScore

1.90

自引率

12.50%

发文量

审稿时长

24 weeks

期刊介绍： Acta Polytechnica is a scientific journal published by CTU in Prague. The main title, Acta Polytechnica, is accompanied by the subtitle Journal of Advanced Engineering, which defines the scope of the journal more precisely - Acta Polytechnica covers a wide spectrum of engineering topics, physics and mathematics. Our aim is to be a high-quality multi-disciplinary journal publishing the results of basic research and also applied research. We place emphasis on the quality of all published papers. The journal should also serve as a bridge between basic research in natural sciences and applied research in all technical disciplines. The innovative research results published by young researchers or by postdoctoral fellows, and also the high-quality papers by researchers from the international scientific community, reflect the good position of CTU in the World University Rankings. We hope that you will ﬁnd our journal interesting, and that it will serve as a valuable source of scientiﬁc information.