{"title":"Xpert Ultra与结核性脑膜炎：政策修订进展？","authors":"M. Caws, S. Dunstan, B. Basnyat","doi":"10.21037/AOI.2018.10.02","DOIUrl":null,"url":null,"abstract":"Tuberculous meningitis (TBM) is a devastating condition with high mortality and survivors are often left with severe neurological sequelae. HIV-associated TBM can have mortality rates exceeding 60% (1). Early diagnosis and initiation of treatment is critical for survival. Unfortunately the diagnosis of TBM can be more of an art than a science, as a recent report in the Lancet by Bahr and colleagues highlights. There is currently no diagnostic test with high sensitivity and specificity.","PeriodicalId":92328,"journal":{"name":"Annals of infection","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.21037/AOI.2018.10.02","citationCount":"0","resultStr":"{\"title\":\"Xpert Ultra and TB meningitis: advancing towards policy revision?\",\"authors\":\"M. Caws, S. Dunstan, B. Basnyat\",\"doi\":\"10.21037/AOI.2018.10.02\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Tuberculous meningitis (TBM) is a devastating condition with high mortality and survivors are often left with severe neurological sequelae. HIV-associated TBM can have mortality rates exceeding 60% (1). Early diagnosis and initiation of treatment is critical for survival. Unfortunately the diagnosis of TBM can be more of an art than a science, as a recent report in the Lancet by Bahr and colleagues highlights. There is currently no diagnostic test with high sensitivity and specificity.\",\"PeriodicalId\":92328,\"journal\":{\"name\":\"Annals of infection\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-02-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.21037/AOI.2018.10.02\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of infection\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21037/AOI.2018.10.02\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of infection","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21037/AOI.2018.10.02","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Xpert Ultra and TB meningitis: advancing towards policy revision?
Tuberculous meningitis (TBM) is a devastating condition with high mortality and survivors are often left with severe neurological sequelae. HIV-associated TBM can have mortality rates exceeding 60% (1). Early diagnosis and initiation of treatment is critical for survival. Unfortunately the diagnosis of TBM can be more of an art than a science, as a recent report in the Lancet by Bahr and colleagues highlights. There is currently no diagnostic test with high sensitivity and specificity.
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