LPMO作为木质纤维素生物质可持续转化的关键酶

IF 0.6 Q4 CHEMISTRY, MULTIDISCIPLINARY

Kemija u Industriji-Journal of Chemists and Chemical Engineers Pub Date : 2023-05-17 DOI:10.15255/kui.2023.010

T. Rezić, Martina Andlar, Ana Vrsalović Presečki

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引用次数: 0

摘要

裂解多糖单加氧酶（LPMO）在制备用于生物炼制的木质纤维素原料中的重要性已在大量研究中得到证实。因此，对LPMO酶进行了研究，以探索酶与底物的相互作用，目的是在生物炼制过程中成功转化生物质。LPMO活性位点还原活化后，他们切割底物，并通过水解酶将其制备为生物量降解。本文基于对LPMO酶结构、LPMO底物偏好和LPMO反应机理的最新研究，描述了LPMO在木质纤维素生物质转化中的作用。这些发现对于在生物炼制生产过程中选择合适的生物工艺条件以实现LPMO活化/稳定具有重要意义。

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LPMO as a Key Enzyme in the Sustainable Conversion of Lignocellulosic Biomass

The importance of the lytic polysaccharide monooxygenase (LPMO) enzyme in the preparation of lignocellulosic raw materials for production in biorefineries has been confirmed in numerous investigations. Therefore, LPMO enzymes were investigated to explore the enzyme-substrate interaction with the aim of successful biomass conversion in biorefinery processes. After reduc - tive activation of LPMOs active site, they cleave the substrate and prepare it for biomass degradation by hydrolytic enzymes. In this paper, the role of LPMO in lignocellulosic biomass conversion is described based on the recent studies of: LPMO enzyme structure, LPMO substrate preferences, and the LPMO reaction mechanism. These findings are important for the selection of suitable bioprocess conditions with the aim of LPMO activation/stabilisation in biorefinery production processes.

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来源期刊

Kemija u Industriji-Journal of Chemists and Chemical Engineers CHEMISTRY, MULTIDISCIPLINARY-

自引率

28.60%

发文量

审稿时长

24 weeks

期刊介绍： Kemija u industriji (Chemistry in industry) is monthly journal which is being published already for almost 60 years continually and from very beginning it is a journal of chemists and chemical engineers. It is official journal of Croatian Society of Chemists and Engineers and of Croatian Chemical Society. It is edited by Croatian Society of Chemists and Engineers.