联合入路治疗椎间孔外延伸较大的颈椎神经鞘瘤

H. Elsobky, A. Zidan, Amin Sabry
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引用次数: 2

摘要

背景资料:约75%的脊髓神经鞘位于硬膜内,10%位于硬膜外,15%完全位于硬膜外。这些肿瘤通常生长缓慢,在出现症状之前会发展到很大。全部或部分位于硬膜外间隙的肿瘤(哑铃瘤)可位于椎管内、椎间孔或椎管外。这些哑铃型约占整个脊柱神经鞘瘤的18%,但它们占几乎一半的颈椎神经鞘瘤。当这些肿瘤有很大的椎间孔外部分时,很难通过单一方法实现完全切除。研究设计:这是一项回顾性研究。目的:评价联合入路切除与椎动脉密切相关的大肿瘤的疗效和安全性。患者和方法:本研究在曼苏拉大学医院对6例年龄22-50岁的颈脊髓鞘瘤患者(男2例,女4例)进行了研究。所有患者术前均采用CT和MRI颈椎和椎动脉血管造影进行临床和影像学评估。采用保留关节突的后路半椎板切除术切除椎管内部分,不影响颈椎稳定性,术后颈部疼痛有限;采用外侧入路切除椎管外延伸部分,避免对椎动脉进行过多操作。术后行颈椎MRI随访。结果:所有肿瘤完全切除的患者均采用联合入路。1例患者术后发生脑脊液渗漏,在腰椎引流管插入后停止。在这项研究中没有死亡率。结论:颈椎管神经鞘有较大外侧突起外成分,需联合入路手术切除,避免椎动脉损伤,保持稳定性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Combined approach for cervical schwannomas with large extraforaminal extension
Background Data : About 75% of Spinal schwannoms are intradural, 10%intra-extradural and 15% are completely extradural . These tumors are usually slowly growing and reach a large size before becoming symptomatic. The tumors which are totally or partially located in the epidural space (dumbbell tumors) are either intraspinal, foraminal or extraspinal. These dumbbell forms represent about 18 % of the total percentage of whole spinal schwannomas, but they are responsible for almost half of the cervical schwannomas When these tumors have large extraforaminal part it become so difficult to achieve total excision through a single approach . Study design : This is a retrospective study. Purpose: To evaluate the efficacy and safety of combined approach for excision of these large tumors closely related to the vertebral artery Patients and Methods : This study was conducted in Mansoura University Hospital on 6 patients two males and four females their age ranged (22-50) years with cervical spinal schwannoms with large lateral extra formaninal component. All patients were assessed clinically and radiologically using CT and MRI cervical spine and vertebral artery angiography before surgery. Posterior approach through a hemilaminectomy with facet preservation was used for excision of the intraspinal part without disturbing the cervical spine stability and with limited postoperative neck pain and a lateral approach for excision the extraspinal extension to avoid so much manibulation on the vertebral artery. Follow up MRI cervical spine was done postoperatively for follow up. Results : Combined approach was done for all patients with complete excision of the tumors . One patient developed CSF Leake after surgery that stopped after lumbar drain insertion . There was no mortality in this study. Conclusion : Cervical spinal schwannoms with large lateral extra formaninal component need combined approach to achieve complete surgical excision , avoid vertebral artery injury and preserve stability .
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