多囊肝患者脑动脉瘤的患病率

IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL
I. Lupescu, S. Iacob, Nicoleta Lupascu, I. Lupescu, C. Pietrăreanu, L. Gheorghe
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引用次数: 0

摘要

背景:众所周知,多囊肾病(PKD)患者发生脑动脉瘤的风险增加,然而,多囊肝病(PLD)患者的这种关联尚未得到很好的研究材料和方法:横断面描述性研究,包括15名在芬迪尼临床研究所胃肠和肝病科诊断为多囊肝的成年患者。在1.5特斯拉MRI上对所有患者进行标准的神经系统检查和大脑MRI。脑成像方案包括T1/T2、T1SE、T2-FLAIR、DWI、SWI、2D-TOF、3D-TOF。结果:绝大多数患者(93%)为女性。平均年龄53±5岁。AD-PKD和多囊肝患者占主导地位(60%)。只有一名被诊断为AD-PKD的患者发现了动脉瘤(其中描述了三个动脉瘤)。在我们的患者组中,脑动脉瘤的总患病率为7%。然而,没有一例孤立性PLD患者被发现有颅内动脉瘤。其他脑部影像学异常频繁但非特异性(主要归因于血管退行性变化)。结论:鉴于这些结果,并且由于我们研究中的患者数量较少,很难理解多囊肝是否确实与脑动脉瘤的风险增加有关。“
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Prevalence of Cerebral Aneurysms in Patients with Polycystic Liver Disease
"Background: It is well known that patients with polycystic kidney disease (PKD) are at increased risk of developing cerebral aneurysms, however, this association has not been well studied for patients with polycystic liver disease (PLD). Material and methods: Cross-sectional descriptive study, which included 15 adult patients diagnosed with polycystic liver disease at the Gastroenterology and Hepatology Department of Fundeni Clinical Institute. Standard neurological exam and brain MRI were performed in all patients on a 1.5 Tesla MRI. Brain imaging protocol included T1/T2, T1SE, T2-FLAIR, DWI, SWI, 2D-TOF, 3D-TOF. Results: The majority of patients (93%) were females. The mean age was 53 ± 5 years old. Patients with AD-PKD and polycystic hepatic disease predominated (60%). Aneurysms were found in only one patient diagnosed with AD-PKD (in whom three aneurysms were described). The overall prevalence of cerebral aneurysms in our patient group was 7%. However, none of the patients with isolated PLD was found to have intracranial aneurysms. Other brain imaging abnormalities were frequent but nonspecific (mostly attributable to vascular-degenerative changes). Conclusions: Given these results, and due to the small number of patients in our study, it is hard to appreciate if polycystic liver disease is indeed associated with an increased risk of cerebral aneurysms. "
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来源期刊
Romanian Journal of Military Medicine
Romanian Journal of Military Medicine MEDICINE, GENERAL & INTERNAL-
自引率
33.30%
发文量
2
审稿时长
12 weeks
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