葡萄糖凝胶预防和治疗新生儿低血糖的效果:一项系统综述和荟萃分析

IF 0.3 Q4 PEDIATRICS
M. Fakhri, R. Farhadi, S. Yousefi, M. Moosazadeh, Melina Ramezanpour, M. Azadbakht
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引用次数: 0

摘要

新生儿低血糖是新生儿病房的主要并发症之一,需要快速诊断和治疗以预防其并发症。葡萄糖凝胶是一种廉价而安全的选择。因此,本系统综述和荟萃分析研究旨在探讨口服葡萄糖凝胶预防和治疗新生儿低血糖的效果。为了找到相关文章,使用标准关键词查阅了包括Barekat Gostar、SID、Magiran、IranDoc在内的国家数据库和包括PubMed、Scopus、Web of Science、Cochrane和Google Scholar在内的国际数据库。使用STATA 14软件对数据进行分析,而P值<0.05被认为是显著的。在9篇样本量为8755名新生儿的文章中,新生儿平均体重在2890至3669克之间。通过正常阴道分娩出生的新生儿比例为61%,而16%的新生儿出生体重较低(2500克以下),16%的新生儿体重较高(4500克以上),51%的母亲患有糖尿病,20%早产,88%为单胎。口服葡萄糖凝胶降低新生儿低血糖的风险OR=0.83(95%CI:0.75-0.93)。然而,口服葡萄糖凝胶治疗新生儿低血糖的OR=0.78(95%CI:0.57-1.07),无统计学意义。口服葡萄糖凝胶可有效预防新生儿低血糖。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of Dextrose Gel in Preventing and Treating Neonatal Hypoglycemia: A Systematic Review and Meta-analysis
Neonatal hypoglycemia is one of the major complications in neonatal wards, requiring rapid diagnosis and treatment to prevent its complications. Dextrose gel is used as a cheap and safe choice. Thus, the present systematic review and meta-analysis study aimed to investigate the effects of oral dextrose gel in preventing and treating neonatal hypoglycemia. To find the relevant articles, the national databases, including Barekat Gostar, SID, Magiran, IranDoc, and international databases, including PubMed, Scopus, Web of Science, Cochrane, and Google Scholar were consulted with standard keywords. The data were analyzed using the STATA 14 software, while the P value < 0.05 was considered significant. In 9 articles with a sample size of 8755 neonates, the mean neonatal weight ranged from 2890 to 3669 g. The share of neonates born through normal vaginal delivery equaled 61%, while 16% had low birth weight (below 2500 g), 16% had high birth weight (above 4500 g), 51% had diabetic mothers, 20% were premature, and 88% were singleton. Oral dextrose gel reduced the risk of neonatal hypoglycemia by OR=0.83 (95% CI: 0.75-0.93). However, neonatal hypoglycemia treatment with oral dextrose gel had an OR=0.78 (95% CI: 0.57-1.07), which was not statistically significant. Oral dextrose gel was effective in preventing neonatal hypoglycemia.
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