择期经皮冠状动脉介入治疗患者中性粒细胞/淋巴细胞比值与心肌损害的关系

Q4 Medicine
F. Emami, F. Pakrad, J. Poorolajal, B. Naghshtabrizi, Hamid Reza Gholalikhani, Azam Alizamir
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引用次数: 0

摘要

背景与目的:中性粒细胞与淋巴细胞的高比值是冠状动脉造影患者心肌梗死风险的一个预测指标。本研究的目的是在评估非紧急血管成形术患者通过干预造成的损害时测量这一比例。材料和方法:一项前瞻性队列研究对2017年在伊朗Hamadan Farshchian心脏中心就诊的122例患者进行了选择性血管成形术。根据中性粒细胞/淋巴细胞比例将患者分为两组。通过检查表和血液检查结果收集数据,包括血管成形术前以及血管成形术后6和12小时的中性粒细胞/淋巴细胞比率、红细胞沉降率(ESR)、c反应蛋白(CRP)、肌酸激酶- mb (CKMB)和肌钙蛋白。采用Stata软件(版本14)进行卡方检验和独立t检验。结果:两组血管成形术前ESR水平比较,差异无统计学意义(P=0.431)。然而,两组在血管成形术后6 h (P=0.001)和12 h (P=0.011)有显著差异。两组治疗前(P=0.310)与治疗后6 h (P=0.186)血钙蛋白水平比较,差异无统计学意义。但两组在血管成形术后12 h差异有统计学意义(P=0.042)。结论:肌钙蛋白水平升高可提高中性粒细胞/淋巴细胞比值和ESR。然而,尽管临床状态有明显变化,但CRP和CKMB水平无显著差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relation of Neutrophil to Lymphocyte Ratio with Myocardial Damage in Patients Undergoing Elective Percutaneous Coronary Intervention
Background and Objective: The high ratio of neutrophils to lymphocytes is a predictor of the risk of myocardial infarction in people who have coronary artery angiography. The purpose of this study was to measure this proportion in the assessment of damage through interventions in patients with non-emergency angioplasty. Materials and Methods: A prospective cohort study was performed on 122 patients referring to Hamadan Farshchian Heart Center, Hamadan, Iran, during 2017 for selected angioplasty. Patients were divided into two groups according to the ratio of neutrophil/ lymphocyte. Data were collected through a checklist and blood test results, including neutrophil/lymphocyte ratio, erythrocyte sedimentation rate (ESR), C-reactive Protein (CRP), Creatine kinase-MB (CKMB), and troponin before angioplasty, as well as 6 and 12 h after angioplasty. The Chi-square test and independent t-test were performed using Stata software (version 14). Results: There was no significant difference between the ESR levels in the two groups before the angioplasty (P=0.431). However, there were significant differences between the two groups 6 h (P=0.001) and 12 h after the angioplasty (P=0.011). There was no significant difference between the blood level of troponin in both groups before (P=0.310) and 6 h after (P=0.186). However, there was a significant difference between the two groups 12 h after the angioplasty (P=0.042). Conclusion: The results showed that an increase in the level of troponin elevated neutrophil/lymphocyte ratio and ESR. However, there was no significant difference in CRP and CKMB levels, although there were significant changes in clinical status.
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来源期刊
CiteScore
0.30
自引率
0.00%
发文量
16
审稿时长
8 weeks
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