收集唾液皮质醇用于大学-公立学校合作娱乐治疗项目的可行性

IF 0.7 Q4 REHABILITATION
Kirstin L. Whitley, S. Lynch, C. L. Franssen, Lindsey S. Sparrock
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引用次数: 0

摘要

本研究的目的是确定唾液皮质醇取样是否会成为社区为残疾儿童服务的RT项目的可行有效的结果测量。本研究中使用的项目在18个月的时间里,为62名3-21岁的当地公立学校特殊教育项目的儿童提供每周10周的RT干预。在每个周期的第1周、第6周和第10周,通过生物拭子收集干预前/后的唾液皮质醇样本(应激反应的生物标志物)。为了确定可行性,在研究期间对唾液样本的收集率、可测量性和可比性进行了跟踪。第一个目标是收集75%的可能的低温瓶,由于实际收集率为56%,因此没有达到目标。参与者的缺席导致62%的低温瓶未收集。然而,在收集到的样本中,95%是可测量的,77%是可比较的,这符合第二个预测,即获得可测量样本的比率为50%或更高。研究人员认为,皮质醇采样与纠正收集错误一样可行,收集错误导致了17%的可能样本损失,这将为未来研究的统计分析提供足够的样本量。订阅TRJ
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Feasibility of Collecting Salivary Cortisol for a Collaborative University- Public School Recreational Therapy Program
The purpose of this study was to determine whether sali-vary cortisol sampling would be a feasible effectiveness outcome measure for a community-based RT program serving children with disabilities. The program utilized in this study provides weekly RT interventions in three 10-week cycles over an 18-month period for 62 children aged 3-21 enrolled in a local public school special edu-cation program. Salivary cortisol sampling, a biomarker for stress response, was collected via bioswab pre/post-intervention on weeks 1, 6, and 10 of each cycle. In or-der to determine feasibility, the collection rate, measur-ability, and comparability of saliva samples were tracked over the study period. The first goal of collecting 75% of the possible cryovials was not met due to an actual col-lection rate of 56%. Participant absence was found to be responsible for 62% of the uncollected cryovials. How-ever, of those collected, 95% were measurable and 77% were comparable, which met the second prediction of achieving measurable samples as a rate of 50% or bet-ter. Researchers deemed cortisol sampling as feasible as correcting collection errors, which caused 17% loss of the overall possible sample, will allow for an adequate sample size for statistical analysis in future studies. Subscribe to TRJ
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来源期刊
自引率
33.30%
发文量
23
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