N. Silivontchik, A. I. Lednik, O. P. Levchuk, L. Plotnikova
{"title":"大分子天冬氨酸转氨酶","authors":"N. Silivontchik, A. I. Lednik, O. P. Levchuk, L. Plotnikova","doi":"10.25298/2616-5546-2021-5-1-25-29","DOIUrl":null,"url":null,"abstract":"Measurement of serum enzyme activity is one of the most common laboratory tests. Increased activity may be caused by abnormal enzymes with a high molecular mass, the so-called macroenzymes. Macroenzymes may be seen in healthy subjects, but can also be related to disease. Macro-aspartate aminotransferase (macro-AST) is a macroenzyme that results from an enzymatic complex consisting of AST linked to serum immunoglobulin (IgA, IgG or both). MacroAST persistence is a rare benign condition. Macro-AST is generally characterized by increased serum AST activity. The article contains analysis of literature data on patients with macro-AST.","PeriodicalId":34878,"journal":{"name":"Gepatologiia i gastroenterologiia","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"MACRO-ASPARTATE AMINOTRANSFERASE\",\"authors\":\"N. Silivontchik, A. I. Lednik, O. P. Levchuk, L. Plotnikova\",\"doi\":\"10.25298/2616-5546-2021-5-1-25-29\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Measurement of serum enzyme activity is one of the most common laboratory tests. Increased activity may be caused by abnormal enzymes with a high molecular mass, the so-called macroenzymes. Macroenzymes may be seen in healthy subjects, but can also be related to disease. Macro-aspartate aminotransferase (macro-AST) is a macroenzyme that results from an enzymatic complex consisting of AST linked to serum immunoglobulin (IgA, IgG or both). MacroAST persistence is a rare benign condition. Macro-AST is generally characterized by increased serum AST activity. The article contains analysis of literature data on patients with macro-AST.\",\"PeriodicalId\":34878,\"journal\":{\"name\":\"Gepatologiia i gastroenterologiia\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-06-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gepatologiia i gastroenterologiia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.25298/2616-5546-2021-5-1-25-29\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gepatologiia i gastroenterologiia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25298/2616-5546-2021-5-1-25-29","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Measurement of serum enzyme activity is one of the most common laboratory tests. Increased activity may be caused by abnormal enzymes with a high molecular mass, the so-called macroenzymes. Macroenzymes may be seen in healthy subjects, but can also be related to disease. Macro-aspartate aminotransferase (macro-AST) is a macroenzyme that results from an enzymatic complex consisting of AST linked to serum immunoglobulin (IgA, IgG or both). MacroAST persistence is a rare benign condition. Macro-AST is generally characterized by increased serum AST activity. The article contains analysis of literature data on patients with macro-AST.
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