Third Ventricle’s Chordoid Gliomas

This is a brief review on the Third Ventricle’s Chordoid Gliomas and their pathogenesis. Chordoid gliomas of the third ventricle are histologically characterized by chordoma-like features. These rare tumors can be seen mostly in the adult patients group specifically in the women population. These solid tumors are well-circumscribed which are adhered to the wall of the third ventricle [1]. Their location is in the anterior part of the third ventricle. These glioma tumors may be extended to reach the suprasellar region. Also, they may cause a hydrocephalus which is obstructive in nature. Regarding differential diagnosis for chordoid glioma, chordoid meningioma and chordoma should be of notice [2]. Chordomas contain physaliphorous cells. They also stain positive for cytokeratins. CD34 and lack of immunoreactivity for Glial fibrillary acidic protein, can also be seen in these tumors. These findings differentiate chordomas from gliomas Chordoid meningiomas show some meningeal features like psammoma bodies and whorl formation. Also, cordoid meningiomas are negative for CD34 and Glial fibrillary acidic protein and positive for Epithelial Abstract Chordoid gliomas are low grade tumors which are most commonly seen in women and in the adult popu-lation. Clinical signs and symptoms of these tumors are mostly related to hydrocephalus which is obstructive in nature. Headache, nausea, visual disturbances, imbalances in the endocrine system and autonomic dysfunction can be seen in these tumors. MRI with contrast is the best diagnostic imaging method for such tumors. The best treatment method for such tumors would be complete surgical resection. In case of incomplete resection, the prognosis can be poorer in comparison with complete surgical resection.