支气管哮喘：当前治疗趋势

Acta Medica Martiniana Pub Date : 2020-04-01 DOI:10.2478/acm-2020-0002

R. Paľová, J. Adamcakova, D. Mokra, J. Mokrý

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引用次数: 2

摘要

哮喘是一种异质性疾病，其病理生理机制尚不清楚。哮喘传统上分为过敏性(外源性)和非过敏性(内在)类型，而过敏性类型的患者对皮质类固醇反应更好。自2013年以来，哮喘的定义发生了变化。最近，对临床考虑和潜在的炎症表型有了更好的了解。定义这些表型已经导致了更具体的临床试验，因此，更个性化和成功的靶向治疗。未来，更多的努力将放在鉴定新的表型特异性生物标志物上，这可能有助于对异质性哮喘患者进行分层。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Bronchial Asthma: Current Trends in Treatment

Abstract Asthma is a heterogenous disease which pathophysiology is still poorly understood. Asthma was traditionally divided into allergic (extrinsic) and non-allergic (intrinsic) types, while patients with allergic type responded better to corticosteroids. Since 2013 the definition of asthma has changed. Recently, better insight into clinical consi -derations and underlying inflammatory phenotypes has been gained. Defining these phenotypes has already led to more specific clinical trials and, therefore, to more personalized and successfully targeted therapy. For future, much more effort is put in identifying new phenotype-specific biomarkers which could be helpful in stratification of heterogeneous patients with asthma.

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来源期刊

Acta Medica Martiniana

自引率

0.00%

发文量

审稿时长

14 weeks

期刊介绍： Acta Medica Martiniana is a medical scientific journal, first published in print form in December 2001. It is a continuation of the journal / almanac Folia Medica Martiniana (1971 - 1996). The journal‘s owner is the Jessenius Faculty of Medicine, Comenius University, Slovakia. Dissemination of research results and scientific knowledge from all areas of medicine and nursing. Stimulation, facilitation and supporting of publication activity for the young medical research and clinical generation. The contributions of young novice authors (PhD students and post-doctorials) are particularly welcome. Acta Medica Martiniana is an open-access journal, with a periodicity of publishing three times per year (Apr/Aug/Dec). It covers a wide range of basic medical disciplines, such as anatomy, histology, biochemistry, human physiology, pharmacology, etc., as well as all clinical areas incl. preventive medicine, public health and nursing. Interdisciplinary and multidisciplinary manuscripts, including papers from all areas of biomedical research, are welcome.