损伤内注射曲安奈德、曲安奈德与透明质酸酶混合液抽吸与外科手术切除前臂神经节的比较研究

Y. Hassan, A. Rather, J. Peer
{"title":"损伤内注射曲安奈德、曲安奈德与透明质酸酶混合液抽吸与外科手术切除前臂神经节的比较研究","authors":"Y. Hassan, A. Rather, J. Peer","doi":"10.4103/mjmsr.mjmsr_57_22","DOIUrl":null,"url":null,"abstract":"Background: Ganglionic cysts are benign tumors of forearm commonly encountered in our day-to-day outdoor practice. This study compares the efficacy, safety, and recurrence rates of triamcinolone, a triamcinolone hyaluronidase mixture, and surgical excision for the treatment of forearm ganglion in a medical college hospital. Materials and Methods: This prospective comparative study was carried out at the SKIMS, Medical College, Hospital, over a period of 3 years. Between January 2018 and January 2021, 96 subjects with forearm ganglion were included and treated in three groups – Group A included patients who had aspiration and injection of triamcinolone; Group B patients had aspiration and injection of mixture of triamcinolone and hyaluronidase; and Group C patients underwent excision under anesthesia. The data were collected and analyzed using SPSS software 22. Results: Among 96 patients who met the inclusion criteria, the mean age was 35.74 years, with a male: female ratio of 0.63. The swelling was the most common clinical presentation recorded in 100% of patients. Swelling with symptoms such as pain and paresthesia was present in 59.38% of the patients, dissatisfaction with cosmetic appearance in 55.21% of the patients, and 36.46% subjects had apprehension of sinister lesion (malignant tumor). 47.92% of patients had aspiration and injection of triamcinolone (Group A), 43.75% of patients had aspiration and injection of triamcinolone-hyaluronidase mixture (Group B), and 8.33% of patients underwent surgical excision (Group C). The difference in recurrence rate was significantly lower in the Group B patients (15.22%) than in the Group A patients (2.38%) (P ≤ 0.05). We observed 100% success rate after surgical excision. No major postprocedure complications occurred in any of the patients. Conclusion: Aspiration and intracystic instillation of a triamcinolone-hyaluronidase mixture is a simple, effective, and safe treatment for ganglion with low recurrence rates. Following an unsuccessful primary therapy of aspiration and injection, surgical excision yielded excellent results.","PeriodicalId":19108,"journal":{"name":"Muller Journal of Medical Sciences and Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparative study between aspiration followed by Intralesional triamcinolone Injection, mixture of triamcinolone and hyaluronidase and surgical excision for the treatment of forearm ganglion in a medical college hospital\",\"authors\":\"Y. Hassan, A. Rather, J. Peer\",\"doi\":\"10.4103/mjmsr.mjmsr_57_22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Ganglionic cysts are benign tumors of forearm commonly encountered in our day-to-day outdoor practice. This study compares the efficacy, safety, and recurrence rates of triamcinolone, a triamcinolone hyaluronidase mixture, and surgical excision for the treatment of forearm ganglion in a medical college hospital. Materials and Methods: This prospective comparative study was carried out at the SKIMS, Medical College, Hospital, over a period of 3 years. Between January 2018 and January 2021, 96 subjects with forearm ganglion were included and treated in three groups – Group A included patients who had aspiration and injection of triamcinolone; Group B patients had aspiration and injection of mixture of triamcinolone and hyaluronidase; and Group C patients underwent excision under anesthesia. The data were collected and analyzed using SPSS software 22. Results: Among 96 patients who met the inclusion criteria, the mean age was 35.74 years, with a male: female ratio of 0.63. The swelling was the most common clinical presentation recorded in 100% of patients. Swelling with symptoms such as pain and paresthesia was present in 59.38% of the patients, dissatisfaction with cosmetic appearance in 55.21% of the patients, and 36.46% subjects had apprehension of sinister lesion (malignant tumor). 47.92% of patients had aspiration and injection of triamcinolone (Group A), 43.75% of patients had aspiration and injection of triamcinolone-hyaluronidase mixture (Group B), and 8.33% of patients underwent surgical excision (Group C). The difference in recurrence rate was significantly lower in the Group B patients (15.22%) than in the Group A patients (2.38%) (P ≤ 0.05). We observed 100% success rate after surgical excision. No major postprocedure complications occurred in any of the patients. Conclusion: Aspiration and intracystic instillation of a triamcinolone-hyaluronidase mixture is a simple, effective, and safe treatment for ganglion with low recurrence rates. Following an unsuccessful primary therapy of aspiration and injection, surgical excision yielded excellent results.\",\"PeriodicalId\":19108,\"journal\":{\"name\":\"Muller Journal of Medical Sciences and Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Muller Journal of Medical Sciences and Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/mjmsr.mjmsr_57_22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Muller Journal of Medical Sciences and Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/mjmsr.mjmsr_57_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

背景:神经节囊肿是我们日常户外活动中常见的前臂良性肿瘤。本研究比较了曲安奈德(一种曲安奈德-透明质酸酶混合物)和外科切除术在医学院医院治疗前臂神经节的疗效、安全性和复发率。材料和方法:这项前瞻性比较研究在SKIMS,医学院,医院进行,为期3年。2018年1月至2021年1月,96名前臂神经节受试者被分为三组进行治疗——A组包括吸入并注射曲安奈德的患者;B组患者吸入并注射曲安奈德和透明质酸酶的混合物;C组在麻醉下切除。数据收集并使用SPSS软件22进行分析。结果:在符合纳入标准的96名患者中,平均年龄为35.74岁,男女比例为0.63。肿胀是100%患者中最常见的临床表现。59.38%的患者出现肿胀并伴有疼痛和感觉异常等症状,55.21%的患者对外表不满意,36.46%的受试者担心有病变(恶性肿瘤)。47.92%的患者抽吸并注射了曲安奈德(A组),43.75%的患者抽吸和注射了曲安醇-透明质酸酶混合物(B组),8.33%的患者接受了手术切除(C组)。B组的复发率(15.22%)明显低于A组(2.38%)(P≤0.05),手术切除后的成功率为100%。所有患者均未出现严重的术后并发症。结论:吸入和囊内滴注曲安奈德透明质酸酶混合物是治疗神经节的一种简单、有效、安全的方法,复发率低。在抽吸和注射的初级治疗失败后,手术切除取得了良好的效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative study between aspiration followed by Intralesional triamcinolone Injection, mixture of triamcinolone and hyaluronidase and surgical excision for the treatment of forearm ganglion in a medical college hospital
Background: Ganglionic cysts are benign tumors of forearm commonly encountered in our day-to-day outdoor practice. This study compares the efficacy, safety, and recurrence rates of triamcinolone, a triamcinolone hyaluronidase mixture, and surgical excision for the treatment of forearm ganglion in a medical college hospital. Materials and Methods: This prospective comparative study was carried out at the SKIMS, Medical College, Hospital, over a period of 3 years. Between January 2018 and January 2021, 96 subjects with forearm ganglion were included and treated in three groups – Group A included patients who had aspiration and injection of triamcinolone; Group B patients had aspiration and injection of mixture of triamcinolone and hyaluronidase; and Group C patients underwent excision under anesthesia. The data were collected and analyzed using SPSS software 22. Results: Among 96 patients who met the inclusion criteria, the mean age was 35.74 years, with a male: female ratio of 0.63. The swelling was the most common clinical presentation recorded in 100% of patients. Swelling with symptoms such as pain and paresthesia was present in 59.38% of the patients, dissatisfaction with cosmetic appearance in 55.21% of the patients, and 36.46% subjects had apprehension of sinister lesion (malignant tumor). 47.92% of patients had aspiration and injection of triamcinolone (Group A), 43.75% of patients had aspiration and injection of triamcinolone-hyaluronidase mixture (Group B), and 8.33% of patients underwent surgical excision (Group C). The difference in recurrence rate was significantly lower in the Group B patients (15.22%) than in the Group A patients (2.38%) (P ≤ 0.05). We observed 100% success rate after surgical excision. No major postprocedure complications occurred in any of the patients. Conclusion: Aspiration and intracystic instillation of a triamcinolone-hyaluronidase mixture is a simple, effective, and safe treatment for ganglion with low recurrence rates. Following an unsuccessful primary therapy of aspiration and injection, surgical excision yielded excellent results.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
12
审稿时长
26 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信