吐温80与卵磷脂乳化剂复配的诺丽叶提取物防晒霜配方

Bianca Levie Tania, Rini Dwiastuti, A. B. S. Lestari, Dewi Setyaningsih
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引用次数: 0

摘要

背景:诺丽叶提取物是一种可作为防晒霜的天然产物。提取物中含有黄酮类化合物,具有抗氧化作用。在这项工作中,使用吐温80和卵磷脂的组合,制备了用诺尼叶提取物配制的防晒霜。目的:本研究的目的是评估吐温80和卵磷脂的组合如何影响乳膏的物理性质,如感官、均匀性、乳液类型、铺展性、粘附性、pH值和室温储存28天的稳定性,并找到最佳配方。方法:本研究在乳膏配方中使用10%的诺丽叶提取物。采用单纯形格子设计(SLD)法测定了不同浓度的两种乳化剂对乳膏的铺展性、附着力和pH值的影响。此外,还用SLD法寻找了最佳配方。结果:不同浓度的乳化剂,即吐温80和卵磷脂的组合,影响了乳膏制剂的物理性能和储存稳定性。吐温80和卵磷脂的相互作用对乳膏的粘附性和铺展性有显著影响;然而,相互作用对pH值的影响并不显著。结论:含有2.5%吐温80和2.5%卵磷脂的配方最能有效地实现乳膏的物理性能,同时在储存过程中保持稳定。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sunscreen Cream Formulation of Noni Leaf Extract (Morinda citrifolia L.) with Emulsifier Combination of Tween 80 and Lecithin
Background: Noni leaf (Morinda citrifolia L.) extract is a natural product that can be used as a sunscreen. The extract contains flavonoids which function act as an antioxidant. In this work, sunscreen cream formulated with noni leaf extract was prepared using a combination of tween 80 and lecithin. Objective: The purpose of this study is to evaluate how the combination of tween 80 and lecithin affects the physical qualities of the cream, such as organoleptic, homogeneity, emulsion type, spreadability, adhesion, pH, and stability over 28 days of storage at room temperature, and to find the best formula. Methods: This study used 10% of noni leaf extract in the cream formulation. The Simplex Lattice Design (SLD) method was used to determine the effect of different concentrations of the two emulsifiers on the cream's spreadability, adhesion, and pH. Furthermore, the SLD was used to find the best formula. Results: The results showed that different concentrations of the emulsifier, which are the tween 80 and lecithin combination, affected the physical properties and storage stability of cream preparations. The interaction of tween 80 and lecithin is having a significant impact on the cream's adhesion and spreadability; however, the effect of the interaction on the pH value was not significant. Conclusion: The formula containing 2.5 % tween 80 and 2.5 percent lecithin was found to be the most effective in fulfilling the cream physical properties while remaining stable during storage.
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