急性中毒患者的人口学和临床特征,重点是心血管并发症;观察性案例系列

Q3 Medicine
P. Ramezannezhad, E. Raeisi, Ayat Roostami-far, Arsalan Khaledi-far
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引用次数: 0

摘要

引言:急性中毒是世界范围内持续存在的健康问题,也是住院最常见的原因之一。对急性中毒发生特征的调查可以有效地规划预防措施和所需的卫生资源。目的:本研究调查了伊朗某省急性中毒的人口统计学和临床特征。患者和方法:设计了一项观察性病例系列研究,调查在六个月内入住两所转诊的三级教学医院的急性中毒患者。前瞻性记录人口统计学数据、包括神经、呼吸和血液动力学状态的生命参数、临床症状和血液分析数据。数据分析采用SPSS 21版软件进行。结果:总共有447名患者被纳入研究(占所有急诊入院患者的3.5%)。患者的平均年龄为33±16(4-88)岁,190名(42.6%)患者为女性。70%的患者年龄在40岁以下。男性患者年龄明显大于女性(P=0.001)。住院死亡率为2.7%。13名(2.9%)患者分别发生循环性休克和呼吸暂停,意识改变影响30%。14%和3.6%的患者观察到动脉血氧饱和度和视力下降。心电图异常的累计患病率为38%。最常见的电解质紊乱是低钙血症(12%),其次是低钾血症(10%);17%的患者受到严重的血液酸中毒的影响。结论:急性中毒是一种高死亡风险的医疗急救。应实施基于多器官的诊断和治疗方法,以尽快处理潜在的致命并发症。应根据目标人群的社会经济状况制定有效的预防计划,以减少急性中毒。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Demographic and clinical features of patients suffering acute intoxication with an emphasis on cardiovascular complications; an observational case series
Introduction: Acute intoxication is an ongoing health issue worldwide and one of the most prevalent causes of hospital admission. Investigation of the features of acute intoxication occurrence allows for effectively planning preventive measures and required health resources. Objectives: The current study investigated acute intoxication’s demographic and clinical characteristics in an Iranian province. Patients and Methods: An observational case-series study was designed to investigate patients suffering from acute intoxication and admitted to two referral tertiary teaching hospitals over six months. Demographic data, vital parameters comprising neurologic, respiratory, and hemodynamic status, clinical symptoms, and blood analysis data were prospectively recorded. Data analysis was conducted using SPSS version 21 software. Results: In total, 447 patients were included in the study (3.5% of all emergency admission). The mean age of patients was 33±16 (4-88) years, and 190 (42.6%) patients were female. Seventy percent of patients were under 40 years. The male patients were significantly older than the female ones (P=0.001). Hospital mortality was 2.7%. Circulatory shock and respiratory apnea occurred separately in 13 (2.9%) patients, and alteration in consciousness affected 30%. Reduced arterial blood saturation and visual acuity were observed in 14% and 3.6% of the patients. A cumulative prevalence of electrocardiogram anomalies of 38% was also observed. The most prevalent electrolyte disorder was hypocalcemia (12%), followed by hypokalemia (10%); 17 % of patients were affected by severe blood acidosis. Conclusion: Acute intoxication is a medical emergency with a high risk of death. A multi-organ-based diagnosis and therapeutic approach should be implemented to manage the potentially lethal complications as soon as possible. Effective preventive planning for reducing acute intoxication should be performed concerning the socioeconomic status of the targeted population.
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来源期刊
Journal of Nephropharmacology
Journal of Nephropharmacology Medicine-Pharmacology (medical)
CiteScore
1.70
自引率
0.00%
发文量
18
审稿时长
4 weeks
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