Bilateral, metachronic ovarian Sertoli–Leydig cell tumour in an 11-year-old patient: A case report

Sertoli–Leydig cell tumours (SLCT) are rare tumours, accounting for less than 0.5% among the ovarian tumours, and occur most frequently in the second and third decades. The majority of them are unilateral and diagnosed at stage I. We report the case of an 11-year-old girl with an abdominal mass and virilisation; left salpingo-oophorectomy was performed and an ovarian SLCT of intermediate differentiation was diagnosed. Twenty nine months later, a new abdominal mass was discovered; a salpingo-oophorectomy was performed and a second SLCT, poorly differentiated, was diagnosed. These tumours represent a rare entity in adolescents and girls, and the bilateral and metachronic presentation makes it exceptional. Despite its low incidence, a high rate of suspicion should be given in the diagnosis of these tumours in very young patients with or without signs of virilisation, and strict surveillance should be maintained in the search for a new related tumour.