皮肤微生物群和皮肤屏障

Q3 Medicine

International Journal of Dermatology and Venerology Pub Date : 2023-08-02 DOI:10.1097/jd9.0000000000000334

Ming-Yang Wu, Xu Yao

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引用次数: 0

摘要

皮肤是人体与外界环境之间的主要屏障。皮肤微生物组在皮肤表面的微生态系统中发挥着重要作用，并介导皮肤屏障功能的多个方面，包括物理、化学、微生物和免疫屏障。在这篇综述中，我们讨论了屏障维持和破坏中宿主-微生物群的相互作用，对特应性皮炎、银屑病和酒渣鼻等皮肤疾病的影响，以及针对皮肤微生物群改善皮肤屏障的最新策略。

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Skin Microbiota and the Skin Barrier

The skin constitutes the primary barrier between the human body and the external environment. The skin microbiome plays an important role in the microecosystem on the skin surface and mediates multiple facets of the skin barrier function, including physical, chemical, microbial, and immune barriers. In this review, we discuss the host–microbiota interactions in barrier maintenance and disruption, implications for skin disorders such as atopic dermatitis, psoriasis, and rosacea, and the latest strategies for targeting the skin microbiota to improve the skin barrier.

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来源期刊

International Journal of Dermatology and Venerology Medicine-Dermatology

CiteScore

1.20

自引率

0.00%

发文量

2950

审稿时长

12 weeks