The use of adjuvants in assisted reproduction treatment

The basic process of in vitro fertilization and related techniques has been overtime expanded by a group of interventions known collectively as “add-ons” or adjuvants. These additional processes vary from simple medications through complex laboratory procedures through to surgical procedures. Almost without exception they have been applied without thorough evaluation by adequately powered clinical trials and universally they add cost to the process. We examine the most commonly used adjuvants under the headings periconceptual medication, laboratory procedures and interventions to enhance implantation.