中毒性表皮坏死松解样亚急性皮肤红斑狼疮1例报告

Serbian Journal of Dermatology and Venereology Pub Date : 2019-12-01 DOI:10.2478/sjdv-2019-0018

J. Perić, B. Lekić, Martina Bosic, D. Škiljević

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引用次数: 2

摘要

皮肤红斑狼疮(LE)包括广泛的皮肤病学表现，包括急性或亚急性皮肤红斑狼疮(10 -like ACLE/SCLE)的毒性表皮坏死松解(TEN)样表现。尽管这些罕见的实体的临床特征和组织学特征可能与TEN非常相似，但一些细微的差异可以帮助区分这些情况。我们报告一例SCLE患者，在长时间强烈的阳光照射后出现与药物无关的TEN样水疱，并重点讨论可用于区分药物诱导的TEN和TEN样表现的不同特征。

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Toxic Epidermal Necrolysis-like Subacute Cutaneous Lupus Erythematosus: a Case Report

Abstract Cutaneous lupus erythematosus (LE) encompasses a wide spectrum of dermatologic manifestations, including toxic epidermal necrolysis (TEN)-like presentations of acute or subacute cutaneous lupus erythematosus (TEN-like ACLE/SCLE). Although the clinical characteristics and histological features of these rare entities may closely mimic TEN, several subtle differences can help in differentiation between these conditions. We report a case of a patient with SCLE which developed drug unrelated TEN-like blisters after prolonged, intensive sun exposure and focus on a discussion of distinctive features that can be used to differentiate drug-induced TEN and TEN-like presentation of ACLE/SCLE.

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来源期刊

Serbian Journal of Dermatology and Venereology

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期刊介绍： Serbian Journal of Dermatology and Venereology is a journal of the Serbian Association of Dermatologists and Venereologists. The journal is published in English, quarterly and intended to provide rapid publication of papers in the field of dermatology and venereology. Manuscripts are welcome from all countries in the following categories: editorials, original studies, review articles, professional articles, case reports, and history of medicine.