不太可能的冠状病毒再感染带来毁灭性后果:通过病例报告解读动态SARS-CoV-2检测结果

Gazeta Medica Pub Date : 2022-01-14 DOI:10.29315/gm.v1i1.446
João Mendes, Cristina Mendes dos Santos, Mário Rui Salvador, Carla V. P. Lima, Joana Cardoso, I. Almeida
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引用次数: 0

摘要

在COVID-19大流行期间,一名40岁妇女因发烧和咳嗽入院。既往有晚期慢性肾病病史。入院时,鼻咽拭子核酸检测呈SARS-CoV-2阳性。11天后,她连续两次检测呈阴性,被认为治愈。八周后,她将接受一名已故捐赠者的肾脏移植手术,但她再次接受了SARS-CoV-2检测,结果呈阳性。在那之后,手术取消了。在我们看来,这个测试不应该进行。通过本病例,我们概述了SARS-CoV-2的传染性、再感染和再激活知识。我们认为,在最近三个月内被认为治愈的患者,如果需要移植或癌症治疗,应该进行免疫抑制治疗。在这些情况下,对大多数患者来说,益处大于最终的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An Unlikely Coronavirus Reinfection with Devastating Consequences: Interpreting Dynamic SARS-CoV-2 Test Result Through a Case Report
A 40-year-old woman was admitted to hospital with fever and cough during the pandemic of COVID-19. Past medical was notable for advanced chronic kidney disease. On admission, nucleic acid testing of a nasopharyngeal swab was positive for SARS-CoV-2. After 11 days she was considered cure with two negative tests in a row. Eight weeks later, she was going to receive a kidney transplant from a deceased donor, but she was tested again for SARS-CoV-2 and the result came out positive. After that, surgery was cancelled. In our opinion, this test should not have been performed. Through this case we overview the knowledge about infectivity, reinfection and reactivation of SARS-CoV-2. We believe who has been considered cured in the last three months should undertake immunosuppression treatment in case of transplant or cancer treatment. In these cases, benefits outweigh the eventual risks for most patients.
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