复发性抗mog相关脑皮质脑炎模拟病毒性脑炎及偏瘫性偏头痛1例

Q4 Medicine

Annals of Child Neurology Pub Date : 2022-12-13 DOI:10.26815/acn.2022.00318

D. Kwon, Soung-Kyung Park, J. Cho, J. Yeom

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引用次数: 0

摘要

髓鞘少突胶质细胞糖蛋白（MOG）是少突胶质表面膜的重要成分[1]。许多研究已将MOG用于免疫介导的脱髓鞘疾病，包括急性播散性脑脊髓炎、视神经炎和横贯性脊髓炎[2]。然而，MOG抗体相关疾病并不局限于脱髓鞘综合征。Ogawa等人[2]于2017年首次描述的大脑皮层脑炎（CCE）是一种新发现的MOG抗体相关疾病表型。抗MOG相关CCE的常见症状包括癫痫发作、头痛、脑炎和皮质症状，如轻瘫[2]。单侧皮质高信号

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A Case of Recurrent Anti-MOG-Associated Cerebral Cortical Encephalitis Mimicking Viral Encephalitis and Hemiplegic Migraine

Myelin oligodendrocyte glycoprotein (MOG) is an essential component of oligodendrocyte sur-face membranes [1]. Numerous studies have im-plicated MOG in immune-mediated demyelinating diseases, including acute disseminated en-cephalomyelitis, optic neuritis, and transverse myelitis [2]. However, MOG antibody-associated diseases are not limited to demyelinating syndromes. Cerebral cortical encephalitis (CCE), first described by Ogawa et al. [2] in 2017, is a newly identified phenotype of MOG antibody-associated disease. Common symptoms of anti-MOG-associated CCE include seizures, headache, encephalitic features, and cortical symptoms, such as paresis [2]. Unilateral cortical hyperintensities

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来源期刊

Annals of Child Neurology Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.50

自引率

0.00%

发文量

审稿时长

8 weeks