黎巴嫩北部献血者戊型肝炎病毒的血清流行病学和风险评估

IF 0.5 Q4 INFECTIOUS DISEASES

Archives of Clinical Infectious Diseases Pub Date : 2022-09-14 DOI:10.5812/archcid-129115

Joyce Ghazzawi, Sara Moubayed, Sara Khalife

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引用次数: 0

摘要

背景:戊型肝炎病毒(HEV)是50%以上急性病毒性肝炎病例的病原体。输血途径已成为戊型肝炎的一种可能传播途径。目的:本研究旨在确定黎巴嫩北部献血者血清中IgM和IgG抗hev的患病率，并评估其发生的相关危险因素。方法:于2020年11月至12月进行横断面研究。采集了78名健康献血者的血液样本。填写一份包含社会人口学、食物消费、生活方式和健康相关特征的标准化问卷，以评估HEV暴露的危险因素。采用酶联免疫吸附试验(ELISA)检测血清中IgM和IgG抗hev抗体。结果:本研究报告血清IgM和IgG抗hev抗体阳性率分别为1.09%(1/78)和12.82%(10/78)。使用私人水井作为饮用水源和前往流行国家的旅行史已被确定为戊型肝炎感染的危险因素(P

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Sero-epidemiology and Risk Assessment of Hepatitis E Virus Among Blood Donors in North Lebanon

Background: Hepatitis E virus (HEV) is the causative agent of over 50% of acute viral hepatitis cases. The blood transfusion route has emerged as a possible route of transmission of HEV. Objectives: This study aimed to determine the seroprevalence of IgM and IgG anti-HEV among blood donors in North Lebanon and to assess the risk factors associated with its occurrence. Methods: A cross-sectional study was conducted from November to December 2020. Blood samples were collected from 78 healthy blood donors. A standardized questionnaire containing sociodemographic, food consumption, lifestyle, and health-related characteristics, was filled out to assess the risk factors of HEV exposure. Serum samples were tested for IgM and IgG anti-HEV by an enzyme-linked immunosorbent assay (ELISA). Results: The seroprevalence of IgM and IgG anti-HEV antibodies was reported in our study, and it reached 1.09% (1/78) and 12.82% (10/78), respectively. The use of private wells as a drinking source and the travel history to endemic countries have been identified as risk factors for HEV infections (P

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来源期刊

Archives of Clinical Infectious Diseases INFECTIOUS DISEASES-

CiteScore

3.40

自引率

0.00%

发文量

期刊介绍： Archives of Clinical Infectious Diseases is a peer-reviewed multi-disciplinary medical publication, scheduled to appear quarterly serving as a means for scientific information exchange in the international medical forum. The journal particularly welcomes contributions relevant to the Middle-East region and publishes biomedical experiences and clinical investigations on prevalent infectious diseases in the region as well as analysis of factors that may modulate the incidence, course, and management of infectious diseases and pertinent medical problems in the Middle East.