利用血清调查研究各系统covid - 19后并发症

Q4 Medicine
Rushikesh Shukla, S. Acharya
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引用次数: 0

摘要

COVID-19是世界上最聪明、最熟练的实践者所害怕的一个词,它带来的破坏比我们想象的要大。COVID-19感染的主要影响是对呼吸和循环系统的影响,这种影响在COVID-19治疗后持续很长时间。即使在完成新冠肺炎药物治疗后,呼吸系统的重要生物标志物也出现了升高。全面评估血液学和炎症生物标志物,如d -二聚体、血清铁蛋白、c反应蛋白(CRP)、血清乳酸脱氢酶(LDH)和白细胞介素-6 (IL-6)水平。还比较了SARS-CoV-2抗体。尽管很少有血清标志物如d -二聚体比其他不可靠的标志物如CRP表现出更多的相关严重并发症。CRP仅仅是炎症的生物标志物并不能粗略地描述病毒造成的破坏的预测。然而,LDH等标记物已被证明在描述导致急性呼吸窘迫综合征(ARDS)的病毒进行性损害方面很有帮助。感染后3个月血清d -二聚体水平升高。少数血液学指标如血清铁蛋白对感染的预后有重要影响,如covid-19等致命疾病的预后对血清铁蛋白等血液学指标有重要的预测价值。外周血IL-6水平可作为COVID-19发展的预测指标。在需要重症监护病房护理的患者中,凝血酶原时间值更高。男性患者血液中可溶性IL-2R、IL-6、铁蛋白、降钙素原、LDH和hsCRP水平高于女性患者。精子样本没有显示出冠状病毒的存在,这证明它对生殖健康的影响很小,对表现也没有损害。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Study of Post-COVID complications in various system using serum investigations
COVID-19, a word feared by the most brilliant and skilled practitioners in the world, Carries more havoc with it than we imagine. The major effects of the COVID-19 infection were on the respiratory and circulatory systems, which lasted for a long period after treatment with COVID-19. Important biomarkers of respiratory system showed elevated levels even after completion of medication for COVID-19. Hematological and inflammatory biomarkers such as D-dimer, serum ferritin, C-reactive protein (CRP), serum lactate dehydrogenase (LDH), and levels of interleukin-6 (IL-6) were thoroughly assessed. The SARS-CoV-2 antibodies were also compared. Although few serum markers like D-dimer has seen to show more associated severe complications than other unreliable markers like CRP. CRP just being the biomarker for inflammation does not grossly describe the forecast of the destruction caused by the virus. However, markers like LDH have shown to be great for describing the progressive damage of the virus leading to acute respiratory distress syndrome (ARDS). The serum levels of D-dimer showed elevation till 3 months' post infection. A few hematological markers like serum ferritin proved to be vital for prognosis of the infection Prognosis of fatal diseases like covid-19 to Hematological markers like Serum ferritin proved their prognostic value. The company of IL-6 in the peripheral blood might be used as a prognosticator of COVID-19 development. In patients who needed intensive care unit care, prothrombin time values were higher. Male patients had higher levels of soluble IL-2R, IL-6, ferritin, procalcitonin, LDH, and hsCRP in their blood than female patients. The sperm samples did not show the presence of coronavirus proving it had just minimal effect on reproductive health and that no damage was seen on the performance as well.
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CiteScore
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