丹麦首都地区住院患者药物相互作用的患病率和特征

Q4 Medicine

Adverse Drug Reaction Bulletin Pub Date : 2021-09-15 DOI:10.1097/FAD.0000000000000057

Hans Kristian Råket Pedersen, A. Sørensen, A. B. Schelde, M. Nyeland, E. Jimenez‐Solem

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引用次数: 0

摘要

以往关于药物相互作用（DDI）流行率的研究大多局限于特定的医院部门。我们在整个医院人群中确定了一年中常见的药物组合和潜在的药物-药物相互作用（pDDI）。经常使用的药物组合包括止痛药、心血管药物和胃肠道药物。新住院患者中pDDI的患病率为2.6%。最常见的pDDI是布洛芬-对乙酰氨基酚、泮托拉唑-对乙酰氨酚和吗啡-对乙酰氨酚。临界pDDI非常罕见，仅占pDDI的0.4%。

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Prevalence and characteristics of drug-drug interactions among hospitalised patients in the Capital Region of Denmark

Summary Previous studies on the prevalence of drug-drug interactions (DDIs) have largely been restricted to specific hospital departments. We identified common drug combinations and potential drug-drug interactions (pDDIs) in an entire hospital population throughout 1 year. Frequently administered drug combinations involved analgesics, cardiovascular medicines and gastrointestinal medicines. The prevalence of pDDIs among newly hospitalised patients was 2.6%. The most common pDDIs were ibuprofen – paracetamol, pantoprazole – paracetamol and morphine – paracetamol. Critical pDDIs were rare and only accounted for 0.4% of pDDIs.

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来源期刊

Adverse Drug Reaction Bulletin Medicine-Pharmacology (medical)

CiteScore

0.70

自引率

0.00%

发文量

期刊介绍： For over 40 years, Adverse Drug Reaction Bulletin has provided comprehensive coverage in the field of adverse drug reactions. Each issue contains an invited article on a topic of current interest, dealing with specific conditions from drug-induced lung disorders to drug-induced sexual dysfunction, or types of drugs from lipid-lowering agents to poisons antidotes. This bimonthly journal"s articles are timely, succinct and fully referenced