特发性肺纤维化(IPF)患者在6周康复计划后生活质量(QoL)的感知改善

S. Senanayake, R. S. P. Fernando, H. F. H. Perera, R. Maddumage, A. G. K. Neranja, K. L. K. T. D. Sandharenu
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摘要

特发性肺纤维化(IPF)是一种慢性、限制生命的疾病,发病后平均预期寿命为05年,没有治疗方法。这些患者需要姑息治疗,康复是提高这些患者生活质量的方法之一。然而,评估肺康复(PR)在改善IPF患者体力活动和生活质量方面的益处的研究仍然有限。因此,本研究旨在评估定制肺部康复计划对IPF患者的身体、生理和心理参数以及生活质量改善的影响。11名IPF受试者接受了6周的肺部康复治疗。访谈者进行了生活质量问卷、6分钟步行测试(6MWT)、增量自行车运动测试,并在康复前后评估了心脏和呼吸参数。训练后6MWT显著增加(训练前312.55±89.99;训练后380.73±59.60)。观察到整体生活质量(2.226±0.026)、呼吸困难(-0.455±0.004)、焦虑(-2.070±0.038)和抑郁(-2.217±0.027)得分显著改善。VO2 max和其他心肺参数没有显著变化,而运动高峰时的SpO2从85.8到86.5没有显著改善。量身定制的肺部康复计划有利于IPF患者功能锻炼能力、呼吸困难和生活质量的短期改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Perceived Improvements of Quality of Life (QoL) among Patients with Idiopathic Pulmonary Fibrosis (IPF) in Response to a 6-Week Rehabilitation Program
Idiopathic pulmonary fibrosis (IPF) is a chronic, life-limiting with an average life expectancy of 05 years following the onset of the disease, with no curative treatments. These patients need palliative care and rehabilitation is one of the methods that can be used to improve quality of life (QoL) among these patients. Yet the research conducted to assess benefits of pulmonary rehabilitation (PR) in terms of improving physical activity and QoL in IPF patients remains limited. Hence this study aims to evaluate the effect of a bespoke pulmonary rehabilitation programme, on the physical, physiological and psychological parameters and improvements of QoL among IPF patients. Eleven (11) subjects with IPF received 6 weeks of pulmonary rehabilitation. An interviewer administered quality of life questionnaire, six-minute walking test (6MWT), Incremental bicycle exercise tests were performed, and cardiac and respiratory parameters were assessed pre- and post-rehabilitation. The 6MWT was significantly increased following training (Pre 312.55 ± 89.99; Post, 380.73 ± 59.60). A significant improvement was observed in overall QoL (2.226 ± 0.026), dyspnoea (-0.455 ± 0.004) anxiety (-2.070 ± 0.038), depression (-2.217 ± 0.027) scores. No significant changes were found in the VO2 max and other cardiopulmonary parameters, while non-significant improvement was seen in SpO2 at peak exercise from 85.8 - 86.5. Bespoke pulmonary rehabilitation program is beneficial in short term improvement of the functional exercise capacity, dyspnoea and QoL among IPF patients.
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