Pembrolizumab诱导的重症肌无力免疫抑制治疗后复发

Medicina interna (Bucharest, Romania : 1991) Pub Date : 2022-04-09 DOI:10.2169/internalmedicine.8554-21

Y. Oshima, Shintaro Fujii, K. Horiuchi

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引用次数: 1

摘要

重症肌无力(MG)是一种免疫相关不良事件(irAE)，作为一种irAE, MG (irAE-MG)通常具有单相病程，在病程中只有少数病例报告出现irAE-MG发作。我们在此报告一例派姆单抗诱导的MG复发症状。irAE-MG是一种罕见的疾病，尚未完全表征，我们的病例表明MG症状可能复发。因此，定期随访是必要的，即使在免疫抑制治疗后症状有所改善。

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Pembrolizumab-induced Myasthenia Gravis Relapse after Immunosuppressive Therapy

Myasthenia gravis (MG) is an immune-related adverse event (irAE), and as an irAE, MG (irAE-MG) generally has a monophasic course, with only a few case reports of irAE-MG flare-ups during the course of the disease. We herein report a case of pembrolizumab-induced MG with relapsing symptoms. irAE-MG is a rare disease that has not yet been fully characterized, and our case shows that MG symptoms may relapse. Therefore, regular follow-up is necessary, even after the symptoms improve with immunosuppressive therapy.

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Medicina interna (Bucharest, Romania : 1991)

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