依恋关系在分离症状发病机制中的作用——文献综述

IF 0.3 Q4 PSYCHIATRY
Dawid Subocz
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引用次数: 1

摘要

目的:综述依恋关系在解离性症状发病机制中的作用。本文以整体的方式整合了环境和遗传因素以及介导解离症状发展的神经生物学过程的知识。材料和方法:使用以下数据库进行文献综述:EBSCO、PsycINFO、PubMed、Google Scholar。使用以下关键词搜索数据库:“依恋风格”、“分离”、“创伤”。这些术语与单词“安全”、“无序”、“表观遗传”、“遗传”和术语“单胺能系统”结合在一起。结果:文献分析表明,依恋关系中的创伤经历与解离症状之间的病理机制是由神经生物学因素介导的。其中包括:单胺类系统内的失调和在情感调节中发挥作用的神经元结构萎缩。讨论和结论:研究表明,依恋关系中的创伤经历是未来出现解离症状的风险因素。目前还缺乏研究来验证依恋体验与调节单胺能系统活性的基因的表观遗传学变化之间的关系。这些过程可能在许多疾病学单位的病因中发挥重要作用,其发展是由解离性症状介导的。未来的研究应该从跨诊断风险因素的角度评估解离,以发展广泛的精神病理学。依恋风格;分解神经生物学
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The role of attachment relationships in the pathogenesis of dissociative symptoms – literature review
Objective: The objective of this paper is to review the literature on the role of the attachment relationship in the pathogenesis of dissociative symptoms. The paper integrates the knowledge of environmental and genetic factors as well as neurobiological processes mediating the development of dissociative symptoms in a holistic way. Material and method: The literature review was performed with the use of the following databases: EBSCO, PsycINFO, PubMed, Google Scholar. The databases were searched using the following keywords: “attachment style”, “dissociation”, “trauma”. These terms were combined with the words ‘secure’, ‘disorganised’, ‘epigenetic’, ‘genetic’ and the term ‘monoaminergic system’. Results: Literature analysis suggests that the pathomechanism linking traumatic experiences in the attachment relationship with dissociative symptoms is mediated by neurobiological factors. These include: dysregulation within monoaminergic systems and atrophy of neuronal structures that play a role in affective regulation. Discussion and conclusions: Research suggests that traumatic experiences in the attachment relationship are a risk factor for the development of dissociative symptoms in the future. There is still a lack of research verifying the relationship between attachment experiences and epigenetic changes in genes regulating the activity of monoaminergic systems. These processes may play an important role in the aetiology of many nosological units, the development of which is mediated by dissociative symptoms. Future research should evaluate dissociation from the perspective of a transdiagnostic risk factor for the development of a broad spectrum of psychopathology. attachment style; dissociation; neurobiology
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CiteScore
1.20
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