高血压患者用药不依从的患病率及预测因素

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
D. Sharma, N. Goel, S. Lehl, D. Walia, S. Puri, Kritee Shukla, Shreyas Mishra
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引用次数: 1

摘要

引言:高血压是一种需要充分治疗的慢性疾病。不坚持服用降压药会导致冠心病和中风并发症。本研究评估了高血压患者药物不依从性的患病率和预测因素。方法:一项横断面研究是在访问北印度一家三级护理医院户外患者科的高血压患者中进行的。经过培训的研究人员在获得研究参与者的书面知情同意书后对他们进行了访谈。一个经过验证的工具,即简短的药物调查问卷,被用来评估药物不依从性。使用Epi-Info Windows版本进行统计分析。结果:共有400名高血压患者参与了这项研究。研究参与者的平均年龄为62.8岁(标准差=11.0)。大约一半(55.0%)的高血压患者患有合并症。抗高血压药物不依从性的患病率为23.8%。逻辑回归模型显示,与其他患者相比,高血压持续时间较短的患者(比值比=2.2[1.2-3.9])和生活在联合家庭的患者(优势比=1.7[1.1-2.8])的药物不依从率较高。结论:近五分之一的研究参与者没有坚持服用降压药物。卫生保健提供者需要制定和实施有效的战略,以提高抗高血压药物的依从性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and predictors of medication nonadherence among hypertensive patients
Introduction: Hypertension is a chronic disease that needs to be treated adequately. Nonadherence to antihypertensive medicines can lead to coronary heart disease and stroke complications. The present study assessed the prevalence and predictors of medication nonadherence among hypertensive patients. Methodology: A cross-sectional study was conducted among hypertensive patients visiting the outdoor patient department of a tertiary care hospital in North India. Trained investigators interviewed the study participants after obtaining their written informed consent. A validated tool, namely the Brief Medication Questionnaire, was used to assess the medication nonadherence. Statistical analyses were performed using the Epi Info version for Windows. Results: A total of 400 hypertensive patients participated in the study. The mean age of study participants was 62.8 years (standard deviation = 11.0). Around half (55.0%) of the hypertensive patients suffered from comorbid disease conditions. The prevalence of antihypertensive medication nonadherence was 23.8%. The logistic regression model revealed that patients having a shorter duration of hypertension (odds ratio = 2.2 [1.2–3.9]) and those living in a joint family (odds ratio = 1.7 [1.1–2.8]) had higher medication nonadherence, as compared to their counterparts. Conclusion: Nearly one-fifth of the study participants were nonadherent to their antihypertension medication. There is a need for designing and implementing effective strategies by health-care providers for increasing antihypertensive medication adherence.
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