Potensi Antelmintik Ekstrak Etanol Daun Mangga Arumanis (Mangifera indica L.) pada Cacing Ascaridia galli dan Raillietina tetragona secara In Vitro

Plants  have potential as a traditional medicine , one of them is arumanis mango ( Mangifera indica L.) which is suspected hav e anthelmintic activity. The aim of this research is to know the anthelmintic activity of ethanol extract of arumanis mango leaves on Ascaridia galli worm and Raillietina tetragona in vitro, to know the effect of increasing extract concentration and to know LC 50 and LT 50 value from extract. The concentration of extract used were 5mg / ml, 25mg/ml and 50mg/ml, normal control (NaCl 0,9%) and positive control (mebendazol e 5 mg/ml). The time and number of worm deaths were observ ed and analyzed using SPSS One Way Anova , Post hoc (LSD) and Probit. The results showed normal controls differ ent significantly with all treatment groups. Concentrations of extracts 25mg/ml and 50mg/ml had time and number of worm deaths that did n’ t differ ent significantly with mebendazole 5mg/ml p=0.466 and p=0.760 at Ascaridia galli , p=0.093 and p=0.566 on Raillietina tetragona , there is an effect of increasing the concentration of extract on the increase of anthelmintic activity. The value of LC 50 extract on Ascaridia galli and Raillietina tetragona are: 2,6mg/ml and 3,1mg/ml, while LT 50 extract value of Ascaridia galli and Raillietina tetragona are: 15 , 2 hours and 2 , 5 hours. The conclusion from this research is Mango arumanis leaves have anthelmintic activity.