强迫症是前驱精神分裂症的一部分

Pub Date : 2018-03-01 DOI:10.12816/0047471
W. A. Asiri, Mundher Almaqbali
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引用次数: 1

摘要

原发性精神分裂症表现为多种精神症状,包括强迫症(OCD)或强迫症状(OCS)。然而,在某些情况下,将强迫症的唯一诊断与前驱精神分裂症区分开来似乎很有挑战性。我们介绍了一名16岁的男性,他有6个月的侵入性图像和恐惧复发史,此外社交活动减少。他作为前驱精神分裂症患者接受治疗,并接受抗精神病药物治疗。他的强迫症减少了,但在随访的两年内,他继续表现出阴性精神分裂症。承认前驱精神分裂症表现的多样性,而不是将症状作为横断面诊断来治疗(尤其是在精神病高危人群中),对于更好的管理至关重要。讨论:本病例说明了官方确定的强迫症诊断的复杂性,该疾病具有明确的标准和有争议的前驱精神分裂症标签,包括强迫症在内的多种表现。一些研究显示,强迫症/OCS在前驱精神分裂症或精神病高危人群中的影响表现为临床障碍更高、抑郁症状更多和自杀。结论:我们的患者被视为前驱性精神分裂症患者,而不是单纯的强迫症患者,这是基于相关特征(冷漠、社会和学业逐渐衰退、精神运动功能减慢和发育异常)。精神分裂症的阳性家族史,以及praecox感觉进一步证实了患者的病情。随后两年的患者病程表明,有必要考虑前驱精神分裂症的完整详细表现,而不是强迫症的现场诊断,以受益于早期干预精神病服务,并将临床恶化降至最低。
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Obsessive - Compulsive Disorder as a Part of Prodromal Schizophrenia
Prodromal schizophrenia presents with a wide variety of psychiatric symptoms including obsessive-compulsive disorder (OCD) or obsessive-compulsive symptoms (OCS). However, this differentiation between a sole diagnosis of OCD and prodromal schizophrenia seems challenging in some settings. We present a sixteen-year-old male with six-months history of recurrent intrusive images and fearfulness, in addition to decreased socialization. He was managed as a case of prodromal schizophrenia and was treated with antipsychotics. His obsessions decreased but he continued to exhibit negative schizophrenia within two years of follow-up. Acknowledging the diversity of prodromal schizophrenia presentations rather than treating symptoms as a cross-sectional diagnosis (especially in high-risk population for psychosis) is crucial for a better management.   DISCUSSION: This case illustrates the complexity of the diagnosis of an officially established disorder that is OCD with well-defined criteria and controversial labeling prodromal schizophrenia with several presentations including OCD. The impact of OCD/OCS among prodromal schizophrenia or at-risk people for psychosis was revealed in some studies by having a higher clinical impairment, more depressive symptoms and suicidality. CONCLUSION: Our patient was managed as a case of prodromal schizophrenia rather than solely OCD based on the associated features (aloofness, progressive social and academic decline, slowed psychomotor functions and dysprosody). Positive family history of schizophrenia in addition to praecox feeling further confirmed the patient’s condition. The following two years of the patient’s course revealed the necessity of considering the full detailed presentation of prodromal schizophrenia rather than the spot diagnosis of OCD to benefit from early intervention psychosis services and minimize the clinical deterioration.
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