具有离散延迟和最优杀虫剂控制的疟疾模型动力学行为

T. Kar, Soovoojeet Jana
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引用次数: 3

摘要

在本文中,我们提出并分析了与疟疾有关的一个简单的三维数学模型。我们分别考虑与易感人群、受感染人群和受感染蚊子相关的三个状态变量。一个离散的延迟参数被纳入考虑与受感染的蚊子潜伏期的时间。我们考虑杀虫剂控制的效果,这是适用于蚊子。计算了所提出模型的基本繁殖数,并表明当该阈值小于单位时,系统将进入无病状态,而当该阈值大于单位时,系统将趋向于地方病状态。另一方面,如果考虑具有时滞的系统,则即使基本繁殖数的数值大于1,也可能存在地方性平衡不稳定的情况。以杀虫剂为控制变量,构造并求解了最优控制问题。最优控制问题保证获得比无控制情况更好的结果。数值实例支持了理论结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dynamical Behavior of a Malaria Model with Discrete Delay and Optimal Insecticide Control
In this paper we have proposed and analyzed a simple three-dimensional mathematical model related to malaria disease. We consider three state variables associated with susceptible human population, infected human population and infected mosquitoes, respectively. A discrete delay parameter has been incorporated to take account of the time of incubation period with infected mosquitoes. We consider the effect of insecticide control, which is applied to the mosquitoes. Basic reproduction number is figured out for the proposed model and it is shown that when this threshold is less than unity then the system moves to the disease-free state whereas for higher values other than unity, the system would tend to an endemic state. On the other hand if we consider the system with delay, then there may exist some cases where the endemic equilibrium would be unstable although the numerical value of basic reproduction number may be greater than one. We formulate and solve the optimal control problem by considering insecticide as the control variable. Optimal control problem assures to obtain better result than the noncontrol situation. Numerical illustrations are provided in support of the theoretical results.
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