前交叉韧带损伤及重建的生物学影响

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-08-23 DOI:10.1016/j.csm.2023.07.003

Chilan B.G. Leite MD, Richard Smith MD, DPhil, Ophelie Z. Lavoie-Gagne MD, Simon Görtz MD, Christian Lattermann MD

引用次数: 0

摘要

由于前十字韧带的愈合能力有限，前十字韧带（ACL）撕裂后通常需要手术干预。然而，机械因素以及损伤和手术引发的炎症反应会影响患者的预后。这篇综述探讨了前交叉韧带损伤和重建生物学的关键方面，包括炎症反应、有限的自发愈合、重建后的继发性炎症以及移植物愈合过程。了解这些生物学机制对于开发新的治疗策略和提高患者的福祉至关重要。通过对这些方面的了解，临床医生和研究人员可以努力提高前交叉韧带撕裂患者的生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.