吡哆醇和吡哆醇治疗长春碱诱导的脑神经病变的疗效——一系列病例

Q4 Medicine

Journal of Nepal Paediatric Society Pub Date : 2022-12-31 DOI:10.3126/jnps.v42i2.42865

Aparajita Gupta, Shuvendu Roy, Prateep Paul

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引用次数: 0

摘要

长春花生物碱以周围神经病变的形式具有神经毒性是众所周知的，然而，脑神经病变并没有得到广泛的认识，尤其是在儿童中。我们在这里描述了三名患有恶性肿瘤的儿童，他们在治疗过程中出现了长春花生物碱诱导的脑神经麻痹，并在服用吡哆醇和吡斯的明后得到解决。长春花生物碱引起的脑神经麻痹是一种潜在的危险但可逆的情况。

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Effectiveness of Pyridostigmine and Pyridoxine in Vinca AlkaloidInduced Cranial Neuropathy – A Case Series

The neurotoxicity of the vinca alkaloids in the form of peripheral neuropathy is well known, however, cranial neuropathy is not widely recognized especially in children. We describe here in three children with malignancies who developed vinca alkaloid induced cranial nerve palsies during treatment which resolved on institution of pyridoxine and pyridostigmine. Vinca-alkaloid-induced cranial nerve palsies represent a potentially dangerous but reversible condition.

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来源期刊

Journal of Nepal Paediatric Society Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.20

自引率

0.00%

发文量

审稿时长

12 weeks