增加周末专科医生强度以改善急诊住院患者的预后:HiSLAC两期混合方法研究

J. Bion, Cassie Aldridge, C. Beet, A. Boyal, Yen-Fu Chen, Michael Clancy, A. Girling, T. Hofer, J. Lord, R. Mannion, P. Rees, Chris Roseveare, L. Rowan, G. Rudge, Jianxia Sun, E. Sutton, C. Tarrant, M. Temple, S. Watson, J. Willars, R. Lilford
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引用次数: 6

摘要

英国国家医疗服务体系的7天服务政策包括10项标准,以改善一周中所有日子获得高质量医疗保健的机会。六项标准针对医院专家,假设他们的缺席导致了与周末住院相关的更高死亡率:“周末效应”。高强度专家领导的急性护理(HiSLAC)合作使用7天服务作为“自然实验”进行了调查。目的是确定周末增加专科医生强度是否能改善急诊住院患者的预后,并探讨机制和成本效益。这是一项两期混合方法的观察性研究。第一年的重点是开发方法。第2-5年包括使用定量和定性方法的纵向研究以及卫生经济学。从2000年到2017年的贝叶斯系统文献综述量化了周末效应。专家强度测量超过5年,使用英国急性医院信托所有专家的自我报告年度点患病率调查,表示为每10个急诊就诊的专家小时数周对周的比率。2007年至2018年的医院事件统计数据提供了周对周死亡率的趋势。通过焦点小组和定性研究人员的现场观察,以及20个信托机构的两个时期的病例记录回顾,定性地探讨了周末效应的机制。在单个信托中检查病例组合差异。卫生经济学模型估计了与增加专家提供相关的成本和结果。在141个急性信托机构中,115个向调查提交了数据,20个提供了4000个病例记录供审查,并参与了定性研究(包括访谈和使用民族志方法元素的观察)。急诊就诊人数和入院人数每年都在增加,超过了专科医生人数的增加;床位数量和住院时间都减少了。死亡率的下降已经趋于平稳;患者出院后死亡的比例有所增加。专家工作时间在2012/13至2017/18年度有所增加。周末专科医生的强度是工作日的一半,但与入院死亡率没有关系。周末入院的病人病情更重(他们有更多的合并症,更多的人需要姑息治疗);根据急性疾病的严重程度进行调整,使周末效应失效。周末住院治疗的效率略高;护理质量(错误、不良事件、总体质量)在周末和工作日一样好,并且随着时间的推移而提高。定性研究人员对医院周末质量的评估与病例记录审稿人在信任水平上一致。全科医生在周末的转诊是工作日的三分之一,并且随着时间的推移进一步下降。观察性研究、可变调查回复率和护理质量的主观评估通过使用差异中差异分析随时间的推移而得到补偿。医院护理正在改善。周末效应与入院前的社区因素有关。出院后死亡率正在上升。决策者应将努力重点放在改善急症和急诊护理上,采用一种“全系统”7天方法,将社会、社区和二级卫生保健结合起来。未来的工作应评估医生在医院和社区急诊护理中的作用,并调查急诊入院的途径和出院后的护理质量。该项目由国家卫生研究所(NIHR)卫生服务和交付研究方案资助,将全文发表在《卫生服务和交付研究》上;第九卷,第13号。请参阅NIHR期刊图书馆网站了解更多项目信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Increasing specialist intensity at weekends to improve outcomes for patients undergoing emergency hospital admission: the HiSLAC two-phase mixed-methods study
NHS England’s 7-day services policy comprised 10 standards to improve access to quality health care across all days of the week. Six standards targeted hospital specialists on the assumption that their absence caused the higher mortality associated with weekend hospital admission: the ‘weekend effect’. The High-intensity Specialist-Led Acute Care (HiSLAC) collaboration investigated this using the implementation of 7-day services as a ‘natural experiment’. The objectives were to determine whether or not increasing specialist intensity at weekends improves outcomes for patients undergoing emergency hospital admission, and to explore mechanisms and cost-effectiveness. This was a two-phase mixed-methods observational study. Year 1 focused on developing the methodology. Years 2–5 included longitudinal research using quantitative and qualitative methods, and health economics. A Bayesian systematic literature review from 2000 to 2017 quantified the weekend effect. Specialist intensity measured over 5 years used self-reported annual point prevalence surveys of all specialists in English acute hospital trusts, expressed as the weekend-to-weekday ratio of specialist hours per 10 emergency admissions. Hospital Episode Statistics from 2007 to 2018 provided trends in weekend-to-weekday mortality ratios. Mechanisms for the weekend effect were explored qualitatively through focus groups and on-site observations by qualitative researchers, and a two-epoch case record review across 20 trusts. Case-mix differences were examined in a single trust. Health economics modelling estimated costs and outcomes associated with increased specialist provision. Of 141 acute trusts, 115 submitted data to the survey, and 20 contributed 4000 case records for review and participated in qualitative research (involving interviews, and observations using elements of an ethnographic approach). Emergency department attendances and admissions have increased every year, outstripping the increase in specialist numbers; numbers of beds and lengths of stay have decreased. The reduction in mortality has plateaued; the proportion of patients dying after discharge from hospital has increased. Specialist hours increased between 2012/13 and 2017/18. Weekend specialist intensity is half that of weekdays, but there is no relationship with admission mortality. Patients admitted on weekends are sicker (they have more comorbid disease and more of them require palliative care); adjustment for severity of acute illness annuls the weekend effect. In-hospital care processes are slightly more efficient at weekends; care quality (errors, adverse events, global quality) is as good at weekends as on weekdays and has improved with time. Qualitative researcher assessments of hospital weekend quality concurred with case record reviewers at trust level. General practitioner referrals at weekends are one-third of those during weekdays and have declined further with time. Observational research, variable survey response rates and subjective assessments of care quality were compensated for by using a difference-in-difference analysis over time. Hospital care is improving. The weekend effect is associated with factors in the community that precede hospital admission. Post-discharge mortality is increasing. Policy-makers should focus their efforts on improving acute and emergency care on a ‘whole-system’ 7-day approach that integrates social, community and secondary health care. Future work should evaluate the role of doctors in hospital and community emergency care and investigate pathways to emergency admission and quality of care following hospital discharge. This project was funded by the National Institute for Health Research (NIHR) Health Services and Delivery Research programme and will be published in full in Health Services and Delivery Research; Vol. 9, No. 13. See the NIHR Journals Library website for further project information.
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