壳聚糖/聚乙烯吡咯烷酮基水凝胶的制备策略及其生物医学应用综述

IF 2.6 4区材料科学 Q3 POLYMER SCIENCE

Polymer-Plastics Technology and Materials Pub Date : 2023-09-04 DOI:10.1080/25740881.2023.2252928

Muhammad Asim Raza, Khurram Shahzad, Shiv Dutt Purohit, Sang Hyun Park, Sung Soo Han

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引用次数: 1

摘要

摘要壳聚糖（CS）和聚乙烯吡咯烷酮（PVP）共混物在制备中具有增强的机械性能、生物相容性、稳定性、抗菌性能和多功能性。由于这些固有的生物相容性和抗菌性能，基于CS/PVP的水凝胶已被用于各种生物医学应用。在此，我们概述了制备具有更好结构和功能性能的CS/PVP水凝胶及其纳米复合材料的最新进展。将CS/PVP与纳米结构相结合，可以改善CS/PVP基质的结构和性能。因此，本文描述了使用CS/PVP水凝胶及其纳米复合材料用于药物递送、蛋白质/基因递送和伤口愈合应用的最新进展。

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The fabrication strategies for chitosan/poly(vinyl pyrrolidone) based hydrogels and their biomedical applications: A focused review

ABSTRACT Chitosan (CS) and poly(vinyl pyrrolidone) (PVP) blend provide enhanced mechanical properties, biocompatibility, stability, antimicrobial properties, and versatility in fabrication. Due to these inherent biocompatible and antimicrobial properties, CS/PVP based hydrogels have been used in various biomedical applications. Herein, we have provided an overview of the recent developments in the fabrication of CS/PVP hydrogels and their nanocomposite with better structural and functional properties. Combining CS/PVP with nano-architectures results in amendments in the structure and properties of the CS/PVP matrices. Hence, recent developments in using CS/PVP hydrogels and their nanocomposites for drug delivery, protein/gene delivery, and wound healing applications are described here.

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来源期刊

Polymer-Plastics Technology and Materials Chemical Engineering-General Chemical Engineering

CiteScore

5.60

自引率

7.40%

发文量

期刊介绍： Polymer-Plastics Technology and Materials provides a forum for the publication of peer-reviewed, English language articles and select reviews on all aspects of polymer-plastics technology and polymeric materials that are industry, semi-commercial, and/or research-oriented. The journal will consider articles on the following general areas: -Polymeric Materials- Polymer Technology and Applications- Bio-related Polymers/Bio-derived Materials- Specialty Polymers- Applied Polymer Science. The journal will consider original research articles, reviews, and book reviews. Proposals for special issues in all the above areas are welcome and should be discussed with the Editor-in-Chief in the first instance.