班加罗尔市区牛皮癣儿童代谢综合征患病率

H. Lakshmi, L. Budamakuntla, C. M. S. Sundar
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摘要

背景:牛皮癣是一种常见的慢性炎症性皮肤病,通常在儿童期发病。越来越多的证据表明,成人牛皮癣与肥胖、代谢综合征(MetS)和相关合并症有关。这种关联引起了人们对牛皮癣儿童长期健康影响的关注,并表明有必要在这一人群中更好地认识、评估和管理超重和肥胖患者及相关代谢疾病。目的:本研究旨在评估儿童牛皮癣中MetS的患病率。材料与方法:这是一项横断面观察性研究,研究对象为6 - 18岁的牛皮癣患儿,患者体表面积为bb10 - 10%。对所有儿童进行met评估和调查。结果:本研究纳入32例儿童,男女比例为5:3,女性发病较早。8名儿童体重指数为>75百分位,其中4名儿童体重指数为>90百分位。4名儿童的腰围在年龄的第90百分位。平均空腹血糖、血清甘油三酯和血清高密度脂蛋白(HDL)分别为89.81±6.56 mg/dl、109.25±36.29 mg/dl和37.78±7.40 mg/dl。32名儿童中有4名符合met的标准,另外14名至少有一项标准。50%(16/32)的人HDL低于40 mg/dl。met患者牛皮癣的平均持续时间更长(4.75年比1.44年,P = 0.005)。结论:小儿牛皮癣与肥胖和MetS相关。伴有牛皮癣的肥胖需要对MetS进行评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of metabolic syndrome among children with psoriasis in urban Bengaluru
Background: Psoriasis is a common, chronic inflammatory dermatosis that often has its onset during childhood. There is increasing evidence that psoriasis in adults is associated with obesity, metabolic syndrome (MetS), and associated comorbidities. Such an association raises concern with regard to the long-term health implications for children with psoriasis and suggests that better awareness, evaluation, and management of overweight and obese patients and associated metabolic disease are warranted in this population. Objectives: The present study was undertaken to evaluate the prevalence of MetS in childhood psoriasis. Materials and Methods: It was a cross-sectional, observational study in children aged between 6 and 18 years with psoriasis involving >10% body surface area. All children were evaluated and investigated for MetS. Results: The study included 32 children, female-to-male ratio was 5:3 with an earlier presentation in females. Body mass index was >75th centile in eight children, and among them, four had >90th centile. The waist circumference of four children was in the 90th percentile for age. Mean fasting plasma glucose, serum triglycerides, and serum high-density lipoprotein (HDL) were 89.81 ± 6.56 mg/dl, 109.25 ± 36.29 mg/dl, and 37.78 ± 7.40 mg/dl, respectively. Four of 32 children met the criteria for MetS, 14 others had at least one criterion. Fifty percent (16/32) of them had HDL lower than 40 mg/dl. The mean duration of psoriasis was more in those with MetS (4.75 years vs. 1.44 years, P = 0.005). Conclusion: Pediatric psoriasis is found to be associated with obesity and MetS. The presence of obesity with psoriasis mandates evaluation for MetS.
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