Azlin Muhammad, Mekadina Bernadus, Rozliana Hanim Mat Hasan, W. Wahid
{"title":"肠道微孢子虫病和沙门氏菌病的混合感染在2岁男孩遗传性免疫缺陷综合征","authors":"Azlin Muhammad, Mekadina Bernadus, Rozliana Hanim Mat Hasan, W. Wahid","doi":"10.22452/JUMMEC.VOL24NO2.5","DOIUrl":null,"url":null,"abstract":"Gastrointestinal microsporidiosis is a major cause of chronic diarrhea in people with acquired immune deficienc syndrome. However, it can also affect individuals with inherited or congenital immunodeficiency. We reported a case of intestinal microsporidiosis and salmonellosis in a young boy with Hyper IgM syndrome. He presented with severe diarrhea and fever for 5 days. Stool examination showed heavy infection of Microsporidia spp. PCR confirmed the species as Enterocytozoon bieneusi. He was treated with albendazole for 25 days which abated the symptoms. To our knowledge, this is the first reported case of intestinal microsporidiosis in inherited immunodeficiency, X-linked Hyper IgM (XHIGM).","PeriodicalId":39135,"journal":{"name":"Journal of the University of Malaya Medical Centre","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A MIXED INFECTION OF INTESTINAL MICROSPORIDIOSIS AND SALMONELLOSIS IN A 2-YEAR-OLD BOY WITH INHERITED IMMUNODEFICIENCY SYNDROME\",\"authors\":\"Azlin Muhammad, Mekadina Bernadus, Rozliana Hanim Mat Hasan, W. Wahid\",\"doi\":\"10.22452/JUMMEC.VOL24NO2.5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Gastrointestinal microsporidiosis is a major cause of chronic diarrhea in people with acquired immune deficienc syndrome. However, it can also affect individuals with inherited or congenital immunodeficiency. We reported a case of intestinal microsporidiosis and salmonellosis in a young boy with Hyper IgM syndrome. He presented with severe diarrhea and fever for 5 days. Stool examination showed heavy infection of Microsporidia spp. PCR confirmed the species as Enterocytozoon bieneusi. He was treated with albendazole for 25 days which abated the symptoms. To our knowledge, this is the first reported case of intestinal microsporidiosis in inherited immunodeficiency, X-linked Hyper IgM (XHIGM).\",\"PeriodicalId\":39135,\"journal\":{\"name\":\"Journal of the University of Malaya Medical Centre\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-09-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the University of Malaya Medical Centre\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22452/JUMMEC.VOL24NO2.5\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the University of Malaya Medical Centre","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22452/JUMMEC.VOL24NO2.5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
A MIXED INFECTION OF INTESTINAL MICROSPORIDIOSIS AND SALMONELLOSIS IN A 2-YEAR-OLD BOY WITH INHERITED IMMUNODEFICIENCY SYNDROME
Gastrointestinal microsporidiosis is a major cause of chronic diarrhea in people with acquired immune deficienc syndrome. However, it can also affect individuals with inherited or congenital immunodeficiency. We reported a case of intestinal microsporidiosis and salmonellosis in a young boy with Hyper IgM syndrome. He presented with severe diarrhea and fever for 5 days. Stool examination showed heavy infection of Microsporidia spp. PCR confirmed the species as Enterocytozoon bieneusi. He was treated with albendazole for 25 days which abated the symptoms. To our knowledge, this is the first reported case of intestinal microsporidiosis in inherited immunodeficiency, X-linked Hyper IgM (XHIGM).