扳机指皮质类固醇注射加和不加局麻药:一项随机、双盲对照试验

The Hand Pub Date : 2019-11-05 DOI:10.1177/1558944719884663
J. Randall Patrinely, Shepard P. Johnson, B. Drolet
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引用次数: 3

摘要

背景:扳机指的一线治疗是皮质类固醇注射。尽管注射溶液通常是用局部麻醉剂制备的,但我们假设接受麻醉剂注射的患者在注射时会感到更多的疼痛。方法:C具有扳机指的患者前瞻性地随机分为2组,接受曲安奈德(1 mL,40 mg)加1%利多卡因加肾上腺素(1 mL)或曲安奈德(1 mL40 mg)加生理盐水(1 mL安慰剂)。病人和外科医生都对治疗臂视而不见。主要结果是注射后立即使用VAS测量疼痛。结果:共有73名患者被纳入研究,共有110个触发指(57个利多卡因加肾上腺素,53个安慰剂)。与安慰剂相比,注射含有利多卡因和肾上腺素的药物后立即疼痛评分明显更高(VAS 3.5 vs 2.0)。结论:在扳机指的治疗中,皮质类固醇注射是有效的,相关疼痛相对较小。这项研究表明,当皮质类固醇包括利多卡因和肾上腺素时,会出现更多的注射相关疼痛。因此,希望减少注射疼痛的外科医生应该排除麻醉剂,但他们应该与患者讨论上述短期麻醉的权衡。仅使用单一药物(即单独使用皮质类固醇)不仅疼痛减轻,而且更简单、有效和安全;因此,这已成为我们首选的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Trigger Finger Corticosteroid Injection With and Without Local Anesthetic: A Randomized, Double-Blind Controlled Trial
Background: The first-line treatment for trigger finger is a corticosteroid injection. Although the injectable solution is often prepared with a local anesthetic, we hypothesize that patients receiving an injection with anesthetic will experience more pain at the time of injection. Methods: C Patients with trigger finger were prospectively randomized into 2 cohorts to receive triamcinolone (1 mL, 40 mg) plus 1% lidocaine with epinephrine (1 mL) or triamcinolone (1 mL, 40 mg) plus normal saline (1 mL, placebo). Both patient and surgeon were blinded to the treatment arm. The primary outcome was pain measured using a (VAS) immediately following the injection. Results: Seventy-three patients with a total of 110 trigger fingers were enrolled (57 lidocaine with epinephrine and 53 placebo). Immediate postinjection pain scores were significantly higher for injections containing lidocaine with epinephrine compared with placebo (VAS 3.5 vs 2.0). Conclusions: In the treatment of trigger finger, corticosteroid injections are effective and have relatively little associated pain. This study shows there is more injection-associated pain when lidocaine with epinephrine is included with the corticosteroid. Therefore, surgeons looking to decrease injection pain should exclude the anesthetic, but they should discuss the trade-off of foregoing short-term anesthesia with patients. Using only a single drug (ie, corticosteroid alone) is not only less painful but is also more simple, efficient, and safe; this has therefore become our preferred treatment method.
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