1-（3-二茂铁-2-甲基吡咯并[1，2-a]喹喔啉-4-基）哌嗪-4-氯化铵的晶体结构

IF 0.1 Q4 CRYSTALLOGRAPHY

X-ray Structure Analysis Online Pub Date : 2021-10-10 DOI:10.2116/xraystruct.37.65

J. Guillon, N. Pinaud, Solène Savrimoutou, M. Marchivie, S. Moreau, Sandra Albenque-Rubio, P. Sonnet

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引用次数: 1

摘要

建立了抗疟药1-(3-二茂铁基-2-甲基吡咯[1,2- a]喹诺沙林-4-基)哌嗪-4-氯化铵的x射线晶体结构。晶胞参数为a = 24.6705(19)Å， b = 24.6705(19)Å， c = 7.4533(6)Å， α = 90°，β = 90°，γ = 90°V = 4536.3(8)Å 3, Z = 8。晶体结构细化到最终值r1 = 0.0354, wr2 = 0.0837。x射线晶体结构分析表明，每个分子都具有分子间N-H···Cl氢键，在铵基和氯阴离子之间相互作用形成四聚体。

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Crystal Structure of 1-(3-Ferrocenyl-2-methylpyrrolo[1,2-a]quinoxalin-4-yl)piperazin-4-ium Chloride

The X-ray crystal structure of the antimalarial 1-(3-ferrocenyl-2-methylpyrrolo[1,2- a ]quinoxalin-4-yl)piperazin-4-ium chloride has been established. It crystallizes in the tetragonal space group P -42 1 c with cell parameters a = 24.6705(19)Å, b = 24.6705(19)Å, c = 7.4533(6)Å, α = 90 ° , β = 90 ° , γ = 90 ° V = 4536.3(8)Å 3 and Z = 8. The crystal structure was refined to final values of R 1 = 0.0354 and wR 2 = 0.0837. An X-ray crystal structure analysis revealed that each molecule features intermolecular N–H···Cl hydrogen bonds interactions between the ammonium group and the chloride anion to form tetramers.

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来源期刊

X-ray Structure Analysis Online CRYSTALLOGRAPHY-

CiteScore

0.60

自引率

50.00%

发文量