巴基斯坦南瓦济里斯坦机构人群术后口服抗生素减少无穿孔阑尾切除术后手术部位感染的频率

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL
Aftab Alam, A. Rehman, Dastageer Waheed, Muhammad Hamayun Khan, Waseem Ahmad, Irum Bashir
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引用次数: 2

摘要

背景:急性阑尾炎是年轻人群中最常见的急腹症病因,而手术部位感染(SSI)是阑尾切除术最常见的并发症。本试验的目的是比较巴基斯坦南瓦济里斯坦地区非穿孔阑尾炎阑尾切除术后口服抗生素与安慰剂在降低手术部位感染(SSI)频率方面的疗效,巴基斯坦,2016年10月1日至2018年11月18日。一百五十(150)名患者被随机分为两组,实验组75人服用抗生素,安慰剂组75人不服用抗生素。年龄组和SSI的存在是两个变量,在名义量表上,通过计数和百分比描述,CI为80%CL。应用McNemar卡方检验来检验假设,以观察实验组和安慰剂组之间在α05时SSI频率方面的差异的显著性。结果:实验组75例病例中有9例(12%,80%CI 7.19-16.80%)存在SSI,安慰剂组75例中有12例(16%,80%CI 10.57-21.42%)存在SSI。McNemar卡方检验显示,在SSI发生率方面,实验组和安慰剂组之间没有显著差异(p=.2482)。结论:在巴基斯坦南瓦济里斯坦地区人群中,术后口服抗生素与安慰剂在降低非穿孔阑尾炎阑尾切除术后手术部位感染(SSI)发生率方面具有可比性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
POST-OPERATIVE ORAL ANTIBIOTICS IN REDUCING FREQUENCY OF SURGICAL SITE INFECTION FOLLOWING NON-PERFORATED APPENDECTOMY IN POPULATION OF SOUTH WAZIRISTAN AGENCY, PAKISTAN
Background: Acute appendicitis is most frequent cause of acute abdomen in younger population, and surgical site infection (SSI) is commonest complication of appendectomy. The objective of this trial was to compare the efficacy of post-operative oral antibiotics versus placebo in reducing the frequency of surgical site infection (SSI) following appendectomy for non-perforated appendicitis in population of South Waziristan Agency, Pakistan.Materials Methods: The randomized placebo trial was conducted at Agency Headquarter Hospital, Wana, South Waziristan, Pakistan from October 1, 2016 to November 18, 2018. One hundred fifty (150) patients were randomly allocated into two groups, 75 in experimental group, to whom antibiotics were given and 75 in placebo group, to whom antibiotics were not given. Age groups and presence of SSI were two variables, being on nominal scale, were described by count and percentage with CI at 80%CL. McNemar chi-square test was applied to test the hypothesis to see the significance of difference between the experimental and placebo groups in terms of frequency of SSI at alpha .05.Results: SSI was present in nine (12%, 80%CI 7.19-16.80%) out of 75 cases in experimental group and in 12 (16%, 80%CI 10.57-21.42%) out of 75 cases in placebo group. McNemar chi-square test showed no significant difference between the experimental and placebo groups in terms of frequency of SSI (p=.2482).Conclusion: The results are comparable for post-operative oral antibiotics versus placebo in reducing the frequency of surgical site infection (SSI) following appendectomy for non-perforated appendicitis in population of South Waziristan Agency, Pakistan.
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来源期刊
Gomal Journal of Medical Sciences
Gomal Journal of Medical Sciences MEDICINE, GENERAL & INTERNAL-
CiteScore
0.60
自引率
80.00%
发文量
37
审稿时长
40 weeks
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