骨断层扫描与双能x线骨密度扫描对骨质疏松症诊断的有效性比较

D. Kumar, S. Jayachandran, N. Thilagavathy
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引用次数: 2

摘要

骨质疏松症是老年人中最常见和最猖獗的代谢性骨疾病之一,尤其影响绝经后妇女。尽管骨小梁比例较高的骨骼(如椎骨、骨盆、跟骨)吸收更快,但皮质骨含量较高的骨骼也会发生吸收,例如下颌骨。低骨密度的牙齿表现包括牙齿松动,牙龈后退,假牙不合适或松动。目的验证骨层析成像(OPGs)应用下颌皮质指数(MCI)识别下颌骨骨密度(BMD)变化的有效性,并证实双能x线骨密度仪(DEXA)扫描股骨颈和脊柱的有效性。材料与方法本横断面研究包括60名男女老年患者。所有患者均在临床指征处接受全景x线片检查。目视分析是根据下颌骨皮质边界的影像学表现进行的,并将结果与DEXA扫描报告进行比较,随后对MCI和BMD的三个等级进行统计分析。结果在我们的研究中,40例C2和C3亚组患者中,67%和20%的患者正常。C2组和C3组中骨质减少的发生率分别为33%和70%,而在C3组中骨质疏松的发生率仅为10%。两组间差异有统计学意义(p = 0.01)。这些发现表明骨密度与皮质形态恶化之间存在着渐进的联系。结论:本研究的目的是牙医能够根据全景x线片的偶然发现,将疑似低骨密度的患者转介给医生进行进一步检查。DEXA与MCI之间存在统计学上显著的相关性,因此后者也可用于筛查BMD变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diagnostic Validity of Orthopantomogram Compared to Dual Energy X-ray Absorptiometry Scan in Detecting Osteoporosis
Abstract Introduction Osteoporosis is one of the most common and rampant metabolic bone disorders among the geriatric, particularly affecting postmenopausal women. Even though resorption tends to occur more rapidly in bones with a higher proportion of trabecular bone (e.g., vertebrae, pelvis, calcaneus), bones with significant cortical bone content also do undergo resorption, for example, mandible. The dental manifestations that may indicate low-bone density include loose teeth, receding gums, and ill-fitting or loose dentures. Objective To validate the efficacy of orthopantomograms (OPGs) in recognizing bone mineral density (BMD) changes of the mandible using mandibular cortical index (MCI) and substantiate the same with dual energy X-ray absorptiometry (DEXA) scan on femoral neck and spine. Materials and Methods This cross-sectional study comprised 60 geriatric patients of both genders. All the patients were subjected to panoramic radiographs wherever clinically indicated. The visual analysis was done based on the radiographic appearance of the mandibular cortical border and results were compared with DEXA scan reports, followed by an analysis of three grades of MCI and BMD statistically. Results In our study, out of 40 patients in C2 and C3 subgroups, 67% and 20% were normal, respectively. The incidence of osteopenia was 33% in the C2 group and 70% in the C3 group, whereas Osteoporosis was present only among 10% of the population in the C3 group. The difference between the groups are statistically significant (p = 0.01). These findings imply that a progressive link exists between BMD and deteriorating cortical morphology. Conclusion The purpose of this study is that dentists will be able to refer patients to physicians of suspected low BMD, based on incidental findings on panoramic radiographs for further examination. There is a statistically significant correlation present between DEXA and MCI, so the latter can also be used for screening BMD changes.
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