舌扁桃体肥大及其物理因素矫正的可能性

IF 0.2
A. Andreev, Sergey Puhlik, O. Melnikov, I. Tagunova, S. Gushcha
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The emphasis on these manifestations, psychosomatic conditions, create a complex of pathological sensations that violate the quality of patients’ life. The goal and objectives of the study are aimed at improving the quality of patients’ life with lingual tonsil hypertrophy (LTH), by developing effective methods of diagnosis and treatment, assessing the role of the immunoregulatory shift in the pathogenesis of LTH of the possibility of their correction by the action of a physical factor (cold destruction). Materials and methods: When examining 850 people who underwent complex research and instrumental diagnostics in connection with the pathology of ENT organs, 119 people (the main group) were diagnosed with different degrees of LTH, with control of 30 healthy people. 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引用次数: 0

摘要

简介:淋巴咽环的组成部分是舌扁桃体(LT),位于舌根上。随着咽部淋巴组织的病理变化,手术切除扁桃体,由于抗原负荷增加,观察到LT的代偿性增加——“舌扁桃体肥大”。这是在与年龄相关的退化变化的背景下观察到的,此时淋巴咽环的其余元件开始发挥抗抗原和适应性活性。发生在中的过程,身体熟悉的LT的结构发生了变化——受体装置从器官产生病理冲动。临床表现的严重程度与LT的增加程度相关。对这些表现的强调,即心身状况,产生了一种复杂的病理感觉,侵犯了患者的生活质量。本研究的目的和目的旨在通过开发有效的诊断和治疗方法,评估免疫调节转变在舌扁桃体肥大(LTH)发病机制中的作用,以及通过物理因素(冷破坏)纠正的可能性,提高舌扁桃体肥大患者的生活质量。材料和方法:在对850名接受与耳鼻喉科器官病理学相关的复杂研究和仪器诊断的人进行检查时,119人(主要组)被诊断为不同程度的LTH,对照组为30名健康人。对76名患者进行了冷冻外科治疗,这些患者使用了通过冷冻破坏治疗舌扁桃体肥大的方法,使用背面带有隔热喷嘴的钩形涂抹器、单独的聚乙烯帽和冷冻装置。结果和讨论:LTH检测到形成扁桃体形态基础的组织体积和质量增加:主要物质是粗纤维层的数量和大小增加、脂肪细胞区和粘液腺的生长。粘膜变薄,发生营养不良退行性变化。增殖率与炎症的严重程度相关,炎症的原因是多因素的,个体的。对微生物和家庭过敏原的敏感性反应增加,血液中对LT组织的抗体含量增加,咽粘膜的微生物致幻症发生变化,非居民微生物群落的植被也发生变化。在56例(73.68%)病例中,冷冻手术治疗的结果是观察到LT组织体积减少。深层被部分吸收,被健康组织取代,表层被排斥,形成萎缩性疤痕或再生,其结构接近器官型。消除了病理冲动的原因,使临床指标正常化,提高了患者的生活质量。结论:LTH应被视为慢性感染和过敏条件下与免疫调节变化相关的生产过程的延续。LTH的局部低温性伴随着其自身物质LT结构的正常化,以及周围组织炎症变化的减少。LT炎症变化的发展是免疫防御系统功能普遍紊乱的局部表现。要想在LTH的治疗中获得持续的积极效果,需要一种强制性的全身免疫校正和激素校正的综合方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lingual tonsils hypertrophy and possibility of its correction by physical factors
Introduction: The component of the lymphopharyngeal ring is the lingual tonsil (LT), located on the root of the tongue. With pathological changes in the lymphoid tissue of the pharynx, surgical removal of the tonsils, as a result of increased antigenic load, a compensatory increase in LT is observed – «lingual tonsillar hypertrophy». This is observed against the background of age-related involutive changes, when the remaining elements of the lymphopharyngeal ring begin to perform anti-antigenic and adaptive activity. The processes taking place in, the structure of the LT, which is familiar to the body, changes - the receptor apparatus creates pathological impulses from the organ. The severity of clinical manifestations correlates with the degree of increase in LT. The emphasis on these manifestations, psychosomatic conditions, create a complex of pathological sensations that violate the quality of patients’ life. The goal and objectives of the study are aimed at improving the quality of patients’ life with lingual tonsil hypertrophy (LTH), by developing effective methods of diagnosis and treatment, assessing the role of the immunoregulatory shift in the pathogenesis of LTH of the possibility of their correction by the action of a physical factor (cold destruction). Materials and methods: When examining 850 people who underwent complex research and instrumental diagnostics in connection with the pathology of ENT organs, 119 people (the main group) were diagnosed with different degrees of LTH, with control of 30 healthy people. Cryosurgical treatment was offered to 76 patients who used the method for treating of lingual tonsil hypertrophy by cryodestruction using a hook-shaped applicator with a heat-insulating nozzle on the back surface, an individual polyethylene cap, and a cryoapparatus. Results and discussions: With LTH, an increase in the volume and mass of tissues forming the morphological basis of the tonsil was detected: the main substance was an increase in the number and size of layers of coarse fibrous fibers, fields of fat cells, and the growth of mucous glands. The mucous membrane, thinning, undergoes dystrophic-degenerative changes. The rate of proliferation correlates with the severity of inflammation, the causes of which are multifactorial, individual. There is an increased sensitivity reaction to microbial and household allergens, an increase in the content of antibodies in the blood to LT tissues, a change in microbiocinosis of the pharyngeal mucosa, and vegetation of non-resident microflora. As a result of cryosurgical treatment in 56 (73.68%) cases, a decrease in the volume of LT tissue was observed. The deep layers, partially absorbed, were replaced by healthy tissues, the surface layers were rejected with the formation of an atrophic scar or regenerate, the structure of which was close to organotypic. The cause of pathological impulse was eliminated, clinical indicators were normalized, the quality of life of patients was improved. Conclusions: LTH should be considered as a continuation of the development of a productive process associated with immunoregulatory changes in chronic infectious and allergic conditions. Local cryogenicity on LTH was accompanied by normalization of the structure of its own substance, LT, and a decrease in inflammatory changes in surrounding tissues. The development of inflammatory changes in LT was a local manifestation of a general disturbance in the functioning of the immune defense system. Achieving a persistent positive effect in the treatment of LTH requires an integrated approach with mandatory systemic immune correction and hormonal correction.
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Balneo Research Journal
Balneo Research Journal REHABILITATION-
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