Cooperation and subject analysis of the research of ω-3 unsaturated fatty acids

Objective To learn the latest progress in the research of ω-3 unsaturated fatty acids and provide references for the related investigator through visualized analysis of the research of ω-3 unsaturated fatty acids published in our country. Methods China Biology Medicine disc was searched by computer from the beginning until December 31, 2017. Bibliographic Item Co-occurrence Mining System (BICOMS) was used to extract and summarize the data of age, author, organization, province and key words and to produce a co-occurrence matrix. NetDraw of Ucinet 6. 0 was employed to draw the social network diagram of the author, organization, province and key words. And cluster analysis of the key words was performed by gCLUTO 2.0. Results A total of 1 165 studies involving 30 provinces and cities, 854 research units, 3 789 authors and 1 016 significative key words were included. The cooperation of author, organization and province needed to be further strengthened. The study focused on 3 aspects: the effects of unsaturated fatty acids on apoptosis/lipid in mice/rats with related genes of diabetes/cardiovascular disease/coronary artery disease; meta-analysis of immunonutrition to improve tumor/inflammation/sepsis; effect of fish oil fat emulsion on interleukin/C reactive protein in pneumonia/lung injury. Conclusions The research of ω-3 unsaturated fatty acids develops rapidly in China, but it is mainly concentrated in a few centers of cooperation agencies. There is little cooperation among different provinces, cities, areas, and organizations and the research topics needs to be further expanded. Key words: ω-3 unsaturated fatty acids; Immunonutrition; Cooperation situation; Subject analysis