{"title":"计算为CRISPR发现和技术赋能","authors":"Stephen Shang, Xiangmeng S. Cai, Lei S. Qi","doi":"10.1038/s43588-022-00321-1","DOIUrl":null,"url":null,"abstract":"CRISPR has revolutionized biomedical and bioengineering research as a programmable genome engineering technology. Computational tools have been integral throughout the discovery of CRISPR biology and the development of CRISPR-based technologies that hold promise to solve many challenges ahead.","PeriodicalId":74246,"journal":{"name":"Nature computational science","volume":"2 9","pages":"533-535"},"PeriodicalIF":18.3000,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Computation empowers CRISPR discovery and technology\",\"authors\":\"Stephen Shang, Xiangmeng S. Cai, Lei S. Qi\",\"doi\":\"10.1038/s43588-022-00321-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"CRISPR has revolutionized biomedical and bioengineering research as a programmable genome engineering technology. Computational tools have been integral throughout the discovery of CRISPR biology and the development of CRISPR-based technologies that hold promise to solve many challenges ahead.\",\"PeriodicalId\":74246,\"journal\":{\"name\":\"Nature computational science\",\"volume\":\"2 9\",\"pages\":\"533-535\"},\"PeriodicalIF\":18.3000,\"publicationDate\":\"2022-09-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature computational science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s43588-022-00321-1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature computational science","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s43588-022-00321-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
Computation empowers CRISPR discovery and technology
CRISPR has revolutionized biomedical and bioengineering research as a programmable genome engineering technology. Computational tools have been integral throughout the discovery of CRISPR biology and the development of CRISPR-based technologies that hold promise to solve many challenges ahead.